WASHINGTON: The US is fast-tracking antimalarial drugs for use as a treatment against the new coronavirus, President Donald Trump said Thursday, following encouraging early results in France and China.
Chloroquine and hydroxychloroquine have not been given a formal green light in the US to fight the pandemic, but the Food and Drug Administration (FDA) said it would work with domestic makers to expand production as it studied their efficacy.
The drugs are already approved for malaria, lupus and rheumatoid arthritis, and doctors in the US may prescribe any drug they believe is appropriate medically.
“We’re going to be able to make that drug available almost immediately, and that’s where the FDA has been so great,” Trump told reporters, referring to both compounds.
The US has recorded 10,755 cases of new coronavirus infection, 154 of them fatal. But authorities expect the number to increase steeply in the coming days because of increased levels of testing after initial delays.
“If there is an experimental drug that is potentially available, a doctor could ask for that drug to be used in a patient. We have criteria for that and very speedy approval for that,” said FDA Commissioner Stephen Hahn.
“As an example, many Americans have read studies and heard media reports about this drug chloroquine, which is an anti-malarial drug.
“That’s a drug that the president directed us to take a closer look at, as to whether an expanded use approach to that could be done to actually see if that benefits patients.”
Chloroquine and hydroxychloroquine are synthetic forms of quinine, which is found in the barks of cinchona trees of Latin America and has been used to treat malaria for centuries.
Some in the wider scientific community have cautioned more research is needed to prove that they really work and are safe for COVID-19.
But French drug maker Sanofi said on Wednesday it was ready to offer the French government millions of doses of hydroxychloroquine, sold under its brand name Plaquenil, in light of a “promising” study carried out by scientist Didier Raoult of the IHU Mediterranee Infection in Marseille.
Raoult reported this week that after treating 24 patients for six days with Plaquenil, the virus had disappeared in all but a quarter of them.
The research has not yet been peer reviewed or published, and Raoult had come under fire by some scientists and officials in his native France for potentially raising false hopes.
“I’m just doing my duty, and I am happy to see that now eight or nine countries recommend chloroquine treatment for patients with this new coronavirus,” he told AFP.
Several clinical trials are also underway in China, where authorities have announced positive results but not yet published their data.
Karine Le Roch, a professor of cell biology at the University of California, Riverside told AFP she was encouraged by recent work in France and China.
“I will say there is a very small number of patients, but if the results are correct, it seems to indeed decrease the viral loads of infected patients,” she said.
“It’s encouraging but we have to make sure the results are accurate and then confirm that with a larger number of patients.”
Scientists understand how these alkaloid compounds work at the cellular level to fight malaria parasites — but it’s not yet known how they are fighting the coronavirus, Le Roch added.
“It’s highly possible that this compound is changing the acidity of the cells infected with the virus,” she told AFP.
“And then the enzymes that are needed for the virus to replicate cannot work as efficiently as they would work without the drug.”
But not everyone is convinced.
Writing in the journal Antiviral Research, French scientists Franck Touret and Xavierde de Lamballerie urged caution, noting that chloroquine had been proposed several times for the treatment of acute viral diseases in humans without success, including HIV.
They added that finding the right dose was crucial because “chloroquine poisoning has been associated with cardiovascular disorders that can be life-threatening.”
US fast-tracking antimalarials to treat coronavirus
https://arab.news/5a3c9
US fast-tracking antimalarials to treat coronavirus
- Some in the wider scientific community have cautioned more research is needed to prove that they really work and are safe for COVID-19
French police remove pro-Palestinian students from the courtyard of Sorbonne university in Paris
- About 50 protesters set up tents at midday Monday at the elite university’s courtyard
PARIS: French police removed dozens of students from the Sorbonne university after pro-Palestinian protesters occupied the main courtyard of the elite institution in Paris on Monday.
About 50 protesters set up tents at midday Monday at the Sorbonne university courtyard in support of Palestinians, echoing similar encampments and solidarity demonstrations across the United States.
Protesters unveiled a giant Palestinian flag and chanted slogans in support of Palestinians in Gaza, as Israel continues its offensive following the deadly Oct. 7 Hamas attack that triggered the Israeli-Hamas war. Police entered the university grounds in the early afternoon and removed them.
About 100 demonstrators took part in the protest near the prestigious university amid heavy police presence that were also guarding the university entrance to prevent students from setting up camp inside again.
Lorelia Frejo, a graduate student at the Sorbonne who joined a protest outside the university, said police used force to remove her peers from the courtyard. “They were peaceful and police took them out with no explanation,” Frejo said. Students in Paris were inspired by the protests at New York’s Columbia University who remain steadfast despite police pressure, she added.
“They (Columbia protesters) are very strong and want to fight for justice and for peace in Palestine,” Frejo said.
The Sorbonne occupies a unique place at the heart of French public and intellectual life. Last week, President Emmanuel Macron chose it as the venue to deliver a speech on his vision of Europe ahead of elections for the European Parliament in June.
Last week protests broke out at another elite university in the French capital region, the Paris Institute of Political Studies, known as Sciences Po, which counts Macron and Prime Minister Gabriel Attal among its many famous alumni.
Tensions had broken out on campus as pro-Palestinian students inspired by Gaza solidarity encampments at campuses in the United States sought to occupy an amphitheater.
On Friday, pro-Palestinian and pro-Israeli demonstrators faced each other in a tense standoff in the street outside the school. Riot police stepped in to separate the opposing groups.
The protest ended peacefully, when students agreed to evacuate the building late on Friday. The head of Sciences Po said an agreement with students had been reached.
Afghan Taliban’s treatment of women under scrutiny at UN rights meeting
- The Taliban say they respect rights in line with their interpretation of Islamic law
- Taliban have barred girls from high school and women from universities and jobs
GENEVA: Afghanistan’s Taliban face criticism over their human rights record at a UN meeting on Monday, with Washington accusing them of systematically depriving women and girls of their human rights.
However, in an awkward first for the UN Human Rights Council, the concerned country’s current rulers will not be present because they are not recognized by the global body.
Afghanistan will instead be represented by an ambassador appointed by the previous US-backed government, which the Taliban ousted in 2021.
In a series of questions compiled in a UN document ahead of the review, the United States asked how authorities would hold perpetrators to account for abuses against civilians, “particularly women and girls who are being systematically deprived of their human rights“?
Britain and Belgium also raised questions about the Taliban’s treatment of women. In total, 76 countries have asked to take the floor at the meeting.
The Taliban say they respect rights in line with their interpretation of Islamic law.
Since they swept back into power, most girls have been barred from high school and women from universities. The Taliban have also stopped most Afghan female staff from working at aid agencies, closed beauty salons, barred women from parks and curtailed travel for women in the absence of a male guardian.
Under the US system, states’ human rights records are subject to peer review in public meetings of the Geneva-based Human Rights Council, resulting in a series of recommendations.
While non-binding, these can draw scrutiny of policies and add to pressure for reform.
The UN Human Rights Council, the only intergovernmental global body designed to protect human rights worldwide, can also mandate investigations whose evidence is sometimes used before national and international courts.
Indian students protest US envoy’s campus talk over Gaza war
- Student-led protest led to university canceling an event involving US ambassador
- Indian students say they stand in solidarity with students protest across US
NEW DELHI: Students at one of India’s most prominent universities gathered in protest over an event involving the US ambassador to New Delhi on Monday, as they stood up against American support for Israel’s war on Gaza.
US Ambassador to India Eric Garcetti was invited for a talk on US-India ties at the Jawaharlal Nehru University in New Delhi on Monday afternoon, which would take place amid protests on American campuses demanding their universities cut financial ties with Israel over its military offensive in Gaza, which has killed more than 34,000 Palestinians.
At the university’s convention center, over 100 students organized by the Jawaharlal Nehru University Student Union protested the invitation of Garcetti, calling out his complicity “in the genocide Israel is currently doing in Palestine.”
JNUSU President Dhananjay told Arab News: “By calling such a person in the university … who is supporting the genocide, we want to tell them that JNU is not silent on this issue and we want to speak up.
“We are protesting against the US support for the genocide in Gaza committed by Israel.”
Hundreds of US college students have been arrested and suspended as peaceful demonstrations calling for a ceasefire in Gaza and divestment from companies linked to Israel spread across American campuses.
The student-led movement comes after nearly six months since Israel began its onslaught on the Gaza Strip, which Tel Aviv said was launched to stamp out the militant group Hamas.
Hundreds of thousands of housing units in the besieged territory have either been completely or partially destroyed, while the majority of public facilities, schools and hundreds of cultural landmarks have been demolished and continue to be targeted in intense bombing operations.
JNU student leaders said they stood in solidarity with the protesting students in the US.
“We are students, and we need to ask questions. If some atrocities are taking place and there are mindless killings going on, speaking out against this should be the responsibility of all sections of society,” Dhananjay said.
“The visuals that we see make us shiver and shake our conscience. If we don’t speak up, then I don’t think we have a right to be a social being.”
At the JNU campus on Monday, the student protest led to a cancellation of the event involving the US envoy.
“We feel happy that we forced the administration to cancel the talks by the ambassador,” JNUSU Vice President Avijit Ghosh told Arab News.
Despite India’s historic support for Palestine, the government has been mostly quiet in the wake of Israel’s deadly siege of Gaza.
When Indians went to the streets in the past months to protest and raise awareness on the atrocities unfolding in Gaza, their demonstrations were dispersed by police and campaigns stifled.
Members of Indian civil society have since come together to challenge their government’s links with Tel Aviv and break Delhi’s silence on Israel’s war crimes against Palestinians, reflecting similar concerns that some university students also felt.
“The US is supporting Israel in the killing of Palestinian people in Gaza. It’s also suppressing students in its country who are raising voice against the genocide in Gaza,” Ghosh said.
“We are agitated that India is being a mute spectator and not taking a clear stand against the ongoing genocide in Gaza.”
Ukraine’s Zelensky urges US to speed up weapons deliveries
KYIV: President Volodymyr Zelensky said on Monday that vital US weapons were starting to arrive in Ukraine in small amounts and that the process needed to move faster as advancing Russian forces were trying to take advantage.
Zelensky told a joint news conference in Kyiv alongside visiting NATO chief Jens Stoltenberg that the situation on the battlefield directly depended on the speed of ammunition supplies to Ukraine.
“Timely support for our army. Today I don’t see anything positive on this point yet. There are supplies, they have slightly begun, this process needs to be sped up,” he said.
Scotland’s Humza Yousaf quits in boost to Labour before UK vote
- Yousaf quit after a week of chaos triggered by his scrapping of a coalition agreement with Scotland’s Greens
- He then failed to secure enough support to survive a vote of no confidence against him expected later this week
LONDON: Scotland’s leader Humza Yousaf resigned on Monday, further opening the door to the UK opposition Labour Party regaining ground in its former Scottish heartlands during a national election expected to be held later this year.
Yousaf said he was quitting as head of the pro-independence Scottish National Party (SNP) and first minister of Scotland’s devolved government after a week of chaos triggered by his scrapping of a coalition agreement with Scotland’s Greens.
He then failed to secure enough support to survive a vote of no confidence against him expected later this week.
Resigning little over a year after he replaced Nicola Sturgeon as first minister and SNP leader, Yousaf said it was time for someone else to lead Scotland.
“I’ve concluded that repairing our relationship across the political divide can only be done with someone else at the helm,” Yousaf said, adding he would continue until a successor was chosen in an SNP leadership contest.
Yousaf abruptly ended a power-sharing agreement between his pro-independence SNP and the Green Party after a row over climate change targets. The SNP’s fortunes have faltered over a funding scandal and the resignation of Sturgeon as party leader last year. There has also been infighting over how progressive its pitch should be as it seeks to woo back voters.
Caught between defending the record of the coalition government and some nationalists’ demands to jettison gender recognition reforms and refocus on the economy, Yousaf was unable to strike a balance that would ensure his survival.
The SNP is losing popular support after 17 years of heading the Scottish government. Earlier this month, polling firm YouGov said the Labour Party had overtaken the SNP in voting intentions for a Westminster election for the first time in a decade.
Labour’s resurgence in Scotland adds to the challenge facing British Prime Minister Rishi Sunak’s Conservative Party which is lagging far behind Labour in UK-wide opinion polls.
The Scottish parliament now has 28 days to choose a new first minister before an election is forced, with former SNP leader John Swinney and Yousaf’s former leadership rival Kate Forbes seen as possible successors.
If the SNP is unable to find a new leader to command support in parliament, a Scottish election will be held. Yousaf, the first Muslim head of government in modern Western Europe, succeeded Sturgeon as first minister in March 2023. Once hugely popular, Sturgeon has been embroiled in a party funding scandal with her husband, who was charged this month with embezzling funds. Both deny wrongdoing.
