Technology only a means, not a solution to healthcare, says biology professor

Panelists participate in the session on innovations in precision healthcare of the Investopia 2023 in Dubai on March 3, 2023. (Supplied)
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Updated 05 March 2023
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Technology only a means, not a solution to healthcare, says biology professor

  • Severino: Healthcare sector witnessing urgent need for intelligence, imagination, creativity
  • Martino: Successful advancement requires academia, government and investors

ABU DHABI: Healthcare is still in an era of imprecision contrary to popular belief, Dr. Gianvito Martino, a professor of experimental biology, told Investopia 2023 on Friday.

Speaking during a session on innovations in precision healthcare, he said doctors and researchers must first understand the molecular mechanisms underlying disorders.

“We are understanding that nature has already solved a lot of mysteries because we are evolving as living organisms for 3.5 billion years,” said Martino.

“What we understood in the past years is that we have to copy what nature is already doing.”

Participating in the session was Dr. Michael Severino, CEO of Tessera Therapeutics, who claimed that one modern game-changer was the ability to study human disease in people rather than animals for better insight.

The necessary technologies did not exist in the past, which made it difficult to examine human subjects, he added.

Severino, who joined Tessera in 2022, brought more than two decades of biopharmaceutical leadership to the company.

He said studying human diseases coupled with expanding the notion of what therapeutics is necessary to keep advancing in the field.

“It’s not just a small molecule, or a therapeutic monoclonal antibody, we have genetic therapies that correct inborn errors in metabolism that can deliver new instructions to cells to keep building abilities we never had before,” explained Severino.

Elaborating on the topic, Martino said the world was entering a ‘natural medicine’ era with it’s current approaches.

“We are using this cutting and paste system, just looking into this, learning how this was done and trying to force the copy,” he said.

“This is what we are doing, and this is what the revolution of the 21st century, (it’s) called the century of biology for this reason.”

Severino said that methodologies have changed, and the healthcare sector is witnessing an urgent need for intelligence, imagination, and creativity in order to come up with revolutionary breakthroughs.

It takes courage to venture out into such projects because the path is never straightforward, he added.

Tessera Therapeutics focuses on advancing gene writing technology and envisions a future where diseases can be treated at their source through an optimal gene-writing system, which deliverers therapeutic instructions to the necessary tissue.

The company’s aim is to alter the human genome and develop precise, durable therapeutic change to cure even the most challenging genetic diseases.

Though there have been evident technological advancements in the healthcare sector, Martino believes that machines are not the solution.

“Technology should be a mean, it’s not the end and it’s not the goal,” he said.

Taking the conversation further, the experimental biology professor said successful advancement in the field requires a combination of academia, a government force, and investors.

Martino has co-authored more than 250 original articles and book chapters.

His scientific interests range from the elucidation of the pathogenic mechanisms of immune-mediated central nervous system disorders to the development of gene and stem cell-based therapies for the treatment of these disorders.

Investopia 2023, which ran from March 2-3, was held in Abu Dhabi, and addressed various topics affecting the global economy today.

The two-day event allowed experts from around the world to exchange knowledge, participate in seminars, and sign memorandums of understanding with local businesses and investors.


Naomi Campbell stuns at Red Sea film premiere of ‘The Absence of Eden’

Updated 03 December 2023
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Naomi Campbell stuns at Red Sea film premiere of ‘The Absence of Eden’

JEDDAH: British supermodel Naomi Campbell was among the many celebrities spotted on the red carpet at the MENA premiere of “The Absence of Eden,” on the third day of Jeddah’s Red Sea International Film Festival.

“I love what Red Sea has become and that it’s growing and growing and growing. And it’s really amazing and phenomenal what the team and Mo (Al-Turki) and Jomana (Al-Rashid) have created,” said Campbell in a video posted on the RSIFF Instagram page.

Starring Marvel actress Zoe Saldana, best known for her role in “The Guardians of the Galaxy,” “The Absence of Eden” marks the feature directing debut of her renowned artist husband Marco Perego. The duo was also spotted at the screening. Also gracing the red carpet was the film’s other star, Garrett Hedlund.

Hedlund plays an ICE agent struggling with the moral dilemmas of his job who unites with an undocumented woman fighting to escape a ruthless cartel, played by Saldana, to save the life of an innocent girl.

The Red Sea festival runs from Nov. 30 to Dec. 9 and boasts 11 categories of films.  

This year’s celebrity-studded festival jury is presided over by director Baz Luhrmann, joined by Swedish-American actor Joel Kinnaman (“Suicide Squad”); Freida Pinto (“Slumdog Millionaire”); Egyptian actor Amina Khalil (“Grand Hotel”) and Spain’s Paz Vega (“Sex and Lucia,” “The OA”).  

The festival began with a gala screening of Dubai-based Iraqi director Yasir Al-Yasiri’s “HWJN,” modelled on a YA novel by Saudi writer Ibraheem Abbas. Set in modern-day Jeddah, “HWJN” follows the story of a kind-hearted jinn — an invisible entity in Islamic tradition — as he discovers the truth about his royal lineage.

Lebanese actress Njeim spoke to Arab News on the red carpet, saying: “The festival marks a turning point for every ambitious Saudi filmmaker, providing excellent support for young talents to showcase their work at international festivals.”


Dhafer L’Abidine on ‘To My Son’ and the magic of Saudi Arabia’s Abha 

Updated 03 December 2023
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Dhafer L’Abidine on ‘To My Son’ and the magic of Saudi Arabia’s Abha 

  • The Tunisian filmmaker and actor’s latest feature was shot in Saudi Arabia, but will ‘resonate anywhere’ 

DUBAI: There are two things that cinema can do better than any other form of artistic expression. First, it allows us to immerse ourselves in parts of the world we’ve never seen, and second, it empowers us to empathize with people we’ve never met. Tunisian megastar Dhafer L’Abidine’s lyrical directorial effort “To My Son,” which will hold its world premiere on December 3 at the Red Sea International Film Festival, excels at both. After scoring a huge global distribution deal the night the fest began, it is now poised to introduce the world to a part of Saudi Arabia never before immortalized on the big screen.  

For L’Abidine, a cross-cultural performer who has long been one of Arab film and television’s most beloved stars, the Saudi-set film is a “love letter” to a country that has fully embraced him. It also marks a welcome return to a festival that helped launched the now-thriving next phase of his career, after his debut feature, the unforgettable politically-charged drama “Ghodwa,” screened to great acclaim at RSIFF 2021.  

But while his last film was a deeply personal exploration of his home country’s political landscape in the wake of the 2011 Tunisian Revolution, “To My Son,” in which he also stars as a British-Saudi father named Feisal, is a leap outside of his lived experience — which has filled the 51-year-old with a range of emotions ahead of the film’s premiere. 

“I’m thrilled to debut ‘To My Son’ in Jeddah. It’s exciting to share this story with this amazing community, a film that aims to capture humanity as well as the beauty of this astounding place. But there’s also a bit of excited nervousness, to be honest, because it’s so different from anything I’ve attempted before,” L’Abidine tells Arab News. 

Tunisian megastar Dhafer L’Abidine in his debut feature ‘Ghodwa,’ which screened at RSIFF in 2021. (Supplied)

“My last film was about Tunisia, it was an idea born from my own culture. But with this film, I’m exploring a place I’m still discovering even years after first coming here. That carries with it a huge responsibility, which I kept at the front in my mind while making it. I knew that I had to do right by this place, these people, and this culture. It’s always challenging to step out of your comfort zone, but I’m always most attracted to making the choices that feel the least safe and easy, because that’s where I thrive,” he continues.  

The film is set primarily in the Abha, a lush, mountainous city in the southwest of the Kingdom that is beloved by Saudis but largely unknown to an international community that has only just begun to explore the country. L’Abidine first found himself there three years ago filming a hit MBC series and was amazed by the place.  

“I really didn’t know what I was in for. You have certain clichés in your head about Saudi Arabia, and then suddenly you find yourself in the middle of these huge green mountains, all with a very distinct quality to them, and so many historical places to discover. You feel really feel you’re somewhere unlike anywhere else in the world. After I left, I couldn’t get this place out of my head,” he explains.  

Dhafer L'Abidine on the set of ‘To My Son.’ (Supplied)

After the release of “Ghodwa,” L’Abidine was meeting with a producer friend, who was himself considering doing a film in Saudi Arabia. He and L’Abidine began to brainstorm, coming up with an idea that became the bones of the story that the film now explores — the story of a Saudi man living in London who, still mourning the death of his wife, decides to return with his son to the home he left 12 years ago. The man’s father, however, still resents him for having left the family, and refuses to accept him back into the fold.  

“As we sat there and explored the concept, it became clear we needed to really highlight that these are people from two different worlds. And Jeddah and Riyadh — as they’re so cosmopolitan and modern — couldn’t capture that difference. I thought, ‘Oh my gosh, this needs to be set in Abha.’ I was brought back to this place that I fell in love with that helped me see Saudi Arabia in a different way and I knew that would be valuable to this story, so I went away to write and it all developed from there,” says L’Abidine.  

   

While Abha helped inspire the story, what became more important to L’Abidine as he developed the film was that it not become a glorified travelogue or tourism campaign. The place, rather, had to serve as a character of sorts on its own, one that could help bring viewers deeper into the emotional journey of the people that live in it. And as he got further into his research of the place’s history, it he realized how universal their struggles really are.  

“Ultimately, this film is an exploration of the humanity that we all share within us, no matter where we’re from. They could be from Abha, Jeddah, Tunis, or Marrakesh. I wanted to make a film that would resonate anywhere, a film that shows that the struggles of the people of Abha — a place cinema has never taken us — are rooted in the same shared experiences that define us all as human beings. We all share stories like this, and the more we focus on that, the closer it brings us,” says L’Abidine.  

In zooming in on characters locked in the struggle between individual fulfillment and duty to family, and in exploring generational divides that require honest discussion in order to get to the heart of what divides them, L’Abidine soon realized this wasn’t just a story about Saudi Arabia, or Arab societies. It was a story about all of us, even himself.  

Quickly, it became clear to him that once again he was making a film about fathers and their children, this time at a period in his life when he is raising a 13-year-old daughter in London who is herself growing up in a world so different that which shaped him back in Tunisia. In the end, as much as he thought he was stepping outside of himself to find the truths of another culture, many of the answers were to be found in his own experience all along.  

“Storytelling is always personal, whether you intend it to be or not. There’s so much in our heads that we have to resolve. And in raising my daughter, there’s so many lessons I’ve had to learn, so much perspective I’ve gained,” says L’Abidine. “I wanted to explore that journey through the main character from both sides, because I think so many people can relate. We all share stories like this.” 


Johnny Depp praises Saudi Arabia's emerging film landscape at the Red Sea International Film Festival

Updated 03 December 2023
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Johnny Depp praises Saudi Arabia's emerging film landscape at the Red Sea International Film Festival

JEDDAH: The ongoing Red Sea International Film Festival played host to Hollywood star Johnny Depp as he graced the MENA premiere of "Jeanne Du Barry," a French historical drama directed by French actress and filmmaker Maïwenn, who also stars in the film.

The festival's second day unfolded with the screening of this opulent portrayal of the life of Jeanne du Barry, a working-class courtesan, featuring Depp as French king Louis XV.

During the festival's third day, Depp expressed his admiration for RSIFF, praising the Kingdom for opening up various expressive and creative outlets, emphasizing on its thriving youth culture.

“I believe that what's happening here in in Saudi with regards to various sort of expressive outlets, creative outlets – art, cinema everything – is opening up sort of beautifully. I also think that since opening up, like giving more opportunity to anyone and everyone. What seems to be really thriving beautifully here is youth culture,” he said to Arab News.

Depp found inspiration in the festival's theme, "Your Story, Your Festival," believing it instills hope and confidence in aspiring filmmakers.

Reflecting on his previous visit to Saudi Arabia, where he attended the MDLBeast music festival, Depp said, “It was  like having some drape taken away from my eyes.”

He expressed enthusiasm about the expanding landscape of the filmmaking industry in the kingdom, praising its beauty, mystery, and rich history.

Depp told Arab News, “Just the idea of shooting the film here. It's so beautiful. And there's such mystery, there's so many beautiful vistas and visually stunning but the history… the history that's here is fascinating.”

“I would come here happily to make a film. The word artist is not one that I use for myself, but you can use it for filmmakers. And everybody seems to understand the artists’ lane,” he said.

The film takes audiences on a journey into the court of Louis XV, where the king becomes infatuated with Jeanne du Barry, a courtesan introduced by an ambitious count seeking royal favor. (Supplied)

The film takes audiences on a journey into the court of Louis XV, where the king becomes infatuated with Jeanne du Barry, a courtesan introduced by an ambitious count seeking royal favor.

Depp delivers a mesmerizing performance as Louis, displaying desiccated charisma, while Maïwenn expertly embodies Jeanne, a woman with wit, intellect, and ambitions of her own. The narrative unfolds into a genuinely devoted partnership, marked by real power, until Louis's demise leads to Jeanne's downfall.

In an interview with Arab News, filmmaker Maïwenn shared her deep connection with her character.

“I have spent years dedicating my time reading about her, all her memories, major events, famous sentences. I know everything by word," she told Arab News.

Maïwenn's dedication to the character spans 16 years, creating a film that she describes as a liberating experience, allowing her subconscious to roam freely.

 

Intrigued by the multifaceted nature of Louis XV, Depp delved into the intricacies of portraying a monarch who had to adapt to different roles within the royal court and on the international stage.

He said during the interview that it was a quite an unusual concept to play a role in French, and his immediate thought was that perhaps a French actor would be more fitting for the role, considering the context.

Despite initial reservations about playing a French character, especially in French, Depp embraced the challenge under Maïwenn's encouragement.

RSIFF extended post-production assistance for the historical drama, marking the foundation's inaugural venture into co-producing a French film. The movie celebrated its global debut at the Cannes Film Festival in May.

During the festival's opening night on Nov.30, Depp was in attendance alongside notable figures such as Will Smith, Michelle Williams, Diane Kruger, Maya Diab, Alessandra Ambrosio, Aseel Omran, and many others. It was a memorable and star-studded event.

The Red Sea International Film Festival continues to Dec. 9 and boasts 11 categories of films: Special Screenings; Red Sea: Competition; Red Sea: Shorts Competition; Festival Favorites; Arab Spectacular; International Spectacular; New Saudi/ New Cinema: Shorts; Red Sea: New Vision; Red Sea: Families and Children; Red Sea: Series and Red Sea: Treasures.


Film AlUla, Stampede Ventures reveal films to be shot in Saudi Arabia under 10-project deal

Updated 03 December 2023
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Film AlUla, Stampede Ventures reveal films to be shot in Saudi Arabia under 10-project deal

JEDDAH: Hollywood movies “Fourth Wall” and “Chasing Red” are set to be filmed in Saudi Arabia’s AlUla in 2024 as part of a 10-project deal between Film AlUla — the Royal Commission for AlUla’s film agency — and global media company Stampede Ventures.

The announcement was made at the Red Sea International Film Festival on Saturday. Stampede Ventures CEO Greg Silverman and executive director of Film AlUla Charlene Deleon-Jones gave further details of the three-year deal, which also includes the previously announced dramatic comedy “K-Pops!”

“Fourth Wall” follows a former child star from a popular TV sitcom who is kidnapped and wakes up in a complete recreation of the show’s set with the rest of the cast, where she must work through her trauma and recreate iconic moments from the series to stay alive and find a way out.

The announcement was made at the Red Sea International Film Festival on Saturday. (AN/ Huda Bashatah) 

Meanwhile, “Chasing Red” is a romance centered around straight-A student Veronica and wealthy playboy Caleb. It is an adaptation of a book by Filipino-Canadian author Isabelle Ronin and is being directed by Jessika Borsiczky, who told Arab News that the story attracted her because “romance is so universal, especially first love, and especially stories about women finding who they are and then finding who they are in relation to the world.”

Stampede Ventures will be among the first to use Film AlUla’s production facility, which includes a 30,000-square-foot soundstage, backlot, production support buildings, workshops, warehouses, recording studio and training and rehearsal space.

Jessika Borsiczky told Arab News that the story attracted her because “romance is so universal.”  (AN/ Huda Bashatah) 

There will be emphasis on using Saudi talent during the production process, Deleon-Jones said, adding: “One of the most significant parts of what we’re doing is the training and development, because this gives us an opportunity to really develop below-the-line crew in somewhere like AlUla, where traditionally the main careers open to you would have been agriculture. We have a young working population who are vibrant and digitally engaged somewhere which is seen as one of the more remote places, (and now) you have this whole new exciting career path.”

The key, she said, was to prove to talent in Saudi Arabia that the film industry is a “sustainable” career choice. Silverman echoed that, saying the deal was “designed specifically so that people can come in and get a chance to prove (themselves) and then there’s another movie coming in the next month that they can be pulled into.”

Silverman is an entertainment industry veteran known for his track record at Warner Bros. where he shepherded over 125 films to more than $38 billion in worldwide box office, most notably the “Harry Potter” series, Christopher Nolan’s “Batman” trilogy, Zack Snyder’s “300,” Todd Phillips’ iconic “Hangover” trilogy, and “Joker.”

Previous Hollywood productions shot in AlUla include the Gerard Butler-led action-thriller “Kandahar,” directed by Ric Roman Waugh, and “Cherry,” starring Tom Holland and directed by Anthony and Joe Russo.


Celebrity-loved footwear designer Amina Muaddi opens pop-up store in Dubai

Updated 02 December 2023
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Celebrity-loved footwear designer Amina Muaddi opens pop-up store in Dubai

DUBAI: Celebrity-loved footwear designer Amina Muaddi revealed this week that she opened a new pop-up store in Dubai at Kite Beach.

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 

A post shared by AMINA MUADDI (@aminamuaddi)

The shoemaker, who is of Jordanian and Romanian descent, has collaborated with clothing retail company Ounass for a four-week pop-up.

“I wanted to create a special experience for our community, a space that feels like an oasis from an outer world,” she wrote, sharing pictures of the place. “Visit the store and shop the collection starting Dec. 1 for the next 30 days. Happy shopping!”

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 

A post shared by AMINA MUADDI (@aminamuaddi)

To celebrate the launch, Ounass hosted an exclusive A-list dinner that was attended by rapper Kanye West, his partner Bianca Censori, American singer Ty Dolla $ign and Lebanese actress Nadine Nassib Njeim.