DUBAI/WASHINGTON: Israeli missiles have hit a site in Iran, ABC News reported late on Thursday, citing a US official, while Iranian state media reported an explosion in the center of the country, days after Iran launched a retaliatory drone strike on Israel.

Commercial flights began diverting their routes early Friday morning over western Iran without explanation as one semiofficial news agency in the Islamic Republic claimed there had been “explosions” heard over the city of Isfahan.

Some Emirates and Flydubai flights that were flying over Iran early on Friday made sudden sharp turns away from the airspace, according to flight paths shown on tracking website Flightradar24.

“Flights over Isfahan, Shiraz and Tehran cities have been suspended,” state media reported.

Iranian officials said its air defenses did shot down several drones but there had been “no missile attack for now” on the country.

The state-run IRNA news agency reported that Iran fired air defense batteries early Friday morning across several provinces after reports of explosions near the city of Isfahan.

Several drones “have been successfully shot down by the country’s air defense, there are no reports of a missile attack for now,” Iran’s space agency spokesman Hossein Dalirian says on X.

The Fars news agency said “three explosions” were heard near the Shekari army airbase near Isfahan.

Iran’s local media also reported that nuclear facilities in Isfahan were “completely secure” after explosions were heard near the area.

“Nuclear facilities in Isfahan province are completely secure,” Tasnim news agency reports, quoting “reliable sources.”

Israel had said it would retaliate against Iran’s weekend attack, which involved hundreds of drones and missiles in retaliation for a suspected Israeli strike on its embassy compound in Syria. Most of the Iranian drones and missiles were downed before reaching Israeli territory.

Several Iranian nuclear sites are located in Isfahan province, including Natanz, centerpiece of Iran’s uranium enrichment program. Isfahan, Isome 350 kilometers (215 miles) south of Iran’s capital, Tehran, is also home to a major air base for the Iranian military.

Meanwhile in Iraq where a number of Iranian-backed militias are based, residents in Baghdad reported hearing sounds of explosions, but the source of the noise was not immediately clear.

In Syria, a local activist group said strikes hit an army position in the south of the country Friday. 

“There were strikes on a Syrian army radar position,” said Rayan Maarouf, who runs the Suwayda24 anti-government website that covers news from Sweida province in the south.

Iranian military positions in Syria had been frequently targetted by Israeli air strikes over the past years. Early this month, an Israeli strike demolished a consular building annex of the Iranian Embassy in Sydia's capital Damascus, killing 13 people, including two generals of Iran's Revolutionary Guards, triggering the Iranian missiles and drones attack on Israel on April 13.

At the United Nations Security Council on Thursday, Iran urged member nations that Israel “must be compelled to stop any further military adventurism against our interests” as the UN secretary-general warned that the Middle East was in a “moment of maximum peril.”

Israel had said it was going to retaliate against Iran’s April 13 missile and drone attack.

Analysts and observers have been raising concerns about the risks of the Israel-Gaza war spreading into the rest of the region.

Oil prices and jumped on the reports of the Israeli strike. Brent crude futures rose 2 percent to $88.86 a barrel, the dollar gained broadly, gold rose 1 percent and S&P 500 futures dropped 1 percent.

Israel’s assault on Gaza began after Palestinian Islamist group Hamas attacked Israel on Oct. 7, killing 1,200, according to Israeli tallies.

Israel’s military offensive has killed over 33,000 Palestinians in Gaza, according to the local health ministry.
Iran-backed groups have declared support for Palestinians, launching attacks from Lebanon, Yemen and Iraq.

An Israeli strike hit the home where a displaced Palestinian family was sheltering in the southern city of Rafah, relatives and neighbors told AFP as they scraped at the soil with their hands.

Al-Arja said the blast killed at least 10 people.

“We retrieved the remains of children and women, finding arms and feet. They were all torn to pieces.

“This is horrifying. It’s not normal,” he said, hauling concrete and broken olive branches from the wreckage. “The entire world is complicit.”

Soon after the war began on Oct. 7, Israel told Palestinians living in the north of Gaza to move to “safe zones” in the territory’s south, like Rafah.

But Israeli Prime Minister Benjamin Netanyahu has since vowed to invade the city, where around 1.5 million people live in shelters, more than half the territory’s population.

“How is Rafah a safe place?” said Zeyad Ayyad, a relative of the victims. He sighed as he cradled a fragment of the remains.

“I heard the bombing last night and then went back to sleep. I did not think it hit my aunt’s house.”

The search for remains was long and painful. The strike left a huge crater and children picked through the rubble while neighbors removed debris, tarpaulin, a pink top.

“We can see them under the rubble and we’re unable to retrieve them,” Al-Arja said. 

“These are people who came from the north because it was said the south is safe.”

“They struck without any warning,” he said.

In a separate strike on the house in Rafah’s Al-Salam neighborhood overnight on Tuesday, rescue crews recovered the corpses of eight family members, including five children and two women, Gaza’s civil defense service said.

“An Israeli rocket hit a house of displaced people,” said resident Sami Nyrab. 

“My sister’s son-in-law, her daughter, and her children were having dinner when an Israeli missile demolished their house over their heads.”