LONDON: Treating COVID-19 patients at home with a commonly-used inhaled asthma drug called budesonide can speed up their recovery, according to UK trial results on Monday which doctors said could change the way the disease is treated around the world.
Researchers behind the trial — known as PRINCIPLE — said the findings were only an interim analysis at this stage, but could soon lead doctors to prescribe budesonide inhalers to patients infected with COVID-19 but not sick enough to be hospitalized.
“For the first time we have high-quality evidence of an effective treatment that can be rolled out across the community for people who are at most risk of developing more severe illness from COVID-19,” said Richard Hobbs, a professor at Britain’s Oxford University who co-led the trial.
He noted that unlike other proven COVID-19 treatments, such as the steroid dexamethasone, budesonide is effective in early stages of COVID-19 and can be used at home. “This is a significant milestone for this pandemic,” he said.
The PRINCIPLE results add to recent evidence from a smaller UK study, which found in February that budesonide reduced recovery time and the need for hospitalization among COVID-19 patients given it within a week of first symptoms.
Budesonide is a safe, relatively cheap and readily available corticosteroid drug used around the world in inhalers to treat asthma and chronic obstructive pulmonary disease (COPD).
“Medical practitioners around the world caring for people with COVID-19 in the community may wish to consider this evidence when making treatment decisions,” said Chris Butler, a family doctor and Oxford professor who co-led the PRINCIPLE study. “It should help people with COVID-19 recover quicker.”
The study involved 961 patients who were randomly assigned to receive inhaled budesonide and compared to 1,819 patients assigned to the usual standard of care. Some 751 people in the budesonide group and 1,028 in the usual care group were SARS-CoV-2 positive and included in the interim analysis.
Doctors asked the budesonide patients to take two puffs on the inhaler, twice a day for a fortnight — giving an inhaled dose of 800 micrograms twice a day for 14 days. All patients were either age 65 plus, or aged over 50 with an underlying health condition that put them at more risk of serious COVID-19.
Interim results, published before peer-review on the medRxiv server, showed that 32% of those on inhaled budesonide, compared to 22% in the usual care group, recovered within the first 14 days and remained well until at least 28 days of follow-up.
Butler’s team said a full analysis with detailed results on time to recovery and hospitalizations would be published when all remaining trial patients have completed follow-up.
Asthma drug budesonide speeds recovery for at-home COVID-19 patients
https://arab.news/peffy
Asthma drug budesonide speeds recovery for at-home COVID-19 patients
- Budesonide is a safe, relatively cheap and readily available drug used to treat asthma
- Doctors said the discovery could change the way Covid-19 is treated around the world
UK police officer charged with showing support for Hamas
- Mohammed Adil, from Bradford in northern England, was arrested last November and charged following an investigation
- Adil, a police constable, has been suspended from his job with West Yorkshire Police and is due to appear in court on Thursday
LONDON: A British police officer has been charged with a terrorism offense for allegedly publishing an image in support of Hamas, a group banned in Britain as a terrorist organization, police said on Wednesday.
Mohammed Adil, 26, from Bradford in northern England, was arrested last November and charged following an investigation by British counter-terrorism officers, Counter Terrorism Policing North East said in a statement.
The police watchdog, the Independent Office for Police Conduct (IOPC), said the inquiries had focused on messages shared on WhatsApp which had concluded the case should be referred to prosecutors.
“On Monday, PC Mohammed Adil, 26, was charged with two counts of publishing an image in support of a proscribed organization, specifically Hamas, contrary to section 13 of the Terrorism Act,” the IOPC statement said. “The offenses are alleged to have taken place in October and November 2023.”
Adil, a police constable, has been suspended from his job with West Yorkshire Police and is due to appear before London Westminster Magistrates’ Court on Thursday.
Since the Oct. 7 attacks by Hamas on Israel, police have arrested and charged a number of people at pro-Palestinian protests in London for showing support for the group, while counter-terrorism commanders say they have also had a large amount of online content referred to them.
Family of 7-year-old girl trampled on boat while crossing Channel feared repatriation to Iraq
- Sara Alhashimi was crushed to death when a large group of men rushed onto an overloaded inflatable dinghy she had boarded with her parents and 2 siblings
- Her father says his family was told they were to be deported to his home country of Iraq after living in Europe for 14 years
LONDON: A seven-year-old Iraqi girl was crushed to death in a small, overcrowded boat as her family, who feared repatriation to Iraq after years living in Europe, attempted to cross the English Channel from France to the UK, the Guardian reported on Wednesday.
Sara Alhashimi was with her father Ahmed Alhashimi, mother Nour Al-Saeed, 13-year-old sister Rahaf and 8-year-old brother Hussam when they boarded an inflatable dinghy at Wimereux, south of Calais, last Tuesday.
But Alhashimi, 41, said that as it set sail, a large group of men rushed onboard and he lost his grip on his daughter. Unable to move because of the crush, he could not reach her and she was trampled. Four other people also died.
Alhashimi said he left Basra around 2010 after he was threatened by an armed group. Sara, his youngest child, was born in Belgium. The family had also lived in Sweden and submitted asylum applications to several EU countries but all were rejected. Their attempt to cross the channel last week was their fourth in two months since arriving in the Pas de Calais region, after police prevented the previous crossings.
Alhashimi told the BBC: “If I knew there was a 1 percent chance that I could keep the kids in Belgium or France or Sweden or Finland I would keep them there.
“All I wanted was for my kids to go to school. I didn’t want any assistance. My wife and I can work. I just wanted to protect them and their childhoods and their dignity.”
Smugglers promised a guaranteed place on a boat carrying 40 migrants for €1,500 ($1,600) per adult and €750 per child, Alhashimi said.
Sara was calm, he added, as he held her hand while they walked from a railway station and then hid in dunes overnight while waiting to board their vessel. The smugglers told the group to inflate the boat shortly before 6 a.m., carry it toward the shore and run as they approached the water.
As they did so, however, a teargas canister thrown by police went off beside them, Alhashimi said, and Sara began to scream. He had been carrying her on his shoulders but once inside the dinghy he put her down so he could help daughter Rahaf get onboard.
As he tried to reach Sara in the increasingly overcrowded boat, Alhashimi said he begged a Sudanese man, who had joined them at the last minute, to get out of the way. He even punched the man, with little effect.
“I just wanted him to move so I could pull my baby up,” he said. “That time was like death itself … We saw people dying. I saw how those men were behaving. They didn’t care who they were stepping on — a child, or someone’s head, young or old. People started to suffocate.
“I could not protect her. I will never forgive myself. But the sea was the only choice I had.”
Alhashimi said was only able to reach Sara after French rescuers had arrived at the boat and removed some of the 112 people onboard.
“I saw her head in the corner of the boat,” he said. “She was all blue. She was dead when we pulled her out. She wasn’t breathing.”
Belgium recently rejected an asylum claim by the family on the grounds that Basra was a safe place for them to return to. They had spent the past seven years living with a friend in Sweden.
“Everything that happened was against my will,” said Alhashimi. “I ran out of options. People blame me and say, ‘how could I risk my daughters?’ But I’ve spent 14 years in Europe and have been rejected.”
Colombia to cut diplomatic ties with Israel
- “Tomorrow (Thursday) diplomatic relations with the state of Israel will be severed... for having a genocidal president,” Petro told a May Day rally in Bogota
- Petro, Colombia’s first leftist president, has also asserted that “democratic peoples cannot allow Nazism to reestablish itself in international politics“
BOGOTA: Colombian President Gustavo Petro said Wednesday his country will sever diplomatic ties with Israel, whose leader he described as “genocidal” over its war in Gaza.
“Tomorrow (Thursday) diplomatic relations with the state of Israel will be severed... for having a genocidal president,” Petro, a harsh critic of the devastating war against Hamas, told a May Day rally in Bogota.
Petro has taken a critical stance on the Gaza assault that followed an unprecedented Hamas attack on southern Israel on October 7 — which resulted in the deaths of some 1,170 people, mostly civilians, according to Israeli figures.
In October, just days after the start of the war, Israel said it was “halting security exports” to Colombia after Petro accused Israeli Defense Minister Yoav Gallant of using language about the people of Gaza similar to what the “Nazis said of the Jews.”
Petro, Colombia’s first leftist president, has also asserted that “democratic peoples cannot allow Nazism to reestablish itself in international politics.”
In February, Petro suspended Israeli weapons purchases after dozens of people died in a scramble for food aid in the war-torn Palestinian territory — an event he said “is called genocide and recalls the Holocaust.”
In the October attack, Hamas militants also took about 250 hostages, 129 of whom remain in Gaza, including 34 Israel says are presumed dead.
Israel’s retaliatory offensive has killed at least 34,568 people in Gaza, mostly women and children, according to the health ministry in the Hamas-run territory.
UK auction house removes Egyptian skulls from sale after outcry
- Lawmaker condemns trade as ‘gross violation of human dignity’
- Items were part of collection owned by English archaeologist Augustus Pitt Rivers
LONDON: A UK auction house has removed 18 ancient Egyptian human skulls from sale amid condemnation by a member of Parliament, The Guardian reported.
Labour MP Bell Ribeiro-Addy said the sale of human remains for any purpose should be outlawed and described the trade as a “gross violation of human dignity.”
Semley Auctioneers in Dorset had listed the skulls with a guide price of £200-£300 ($250-$374) for each lot. The collection included 10 male skulls, five female and three of an uncertain sex.
Some of the skulls were listed as coming from Thebes and dating back to 1550 B.C.
They were originally collected by Augustus Henry Lane Fox Pitt Rivers, an English soldier and archaeologist who established the Pitt Rivers Museum in Oxford, which contains about 22,000 items.
After being housed at a separate private museum on his estate, the skulls were sold as part of a larger collection to his grandson, George Pitt Rivers, who was interned during the Second World War for supporting fascist leader Oswald Mosley.
Ribeiro-Addy said: “This despicable trade perpetuates a dark legacy of exploitation, colonialism and dehumanization. It is a gross violation of human dignity and an affront to the memory of those whose lives were unjustly taken, or whose final resting places were desecrated.
“We cannot allow profit to be made from the exploits of those who often hoped to find evidence for their racist ideology. It is imperative that we take decisive action to end such practices and ensure that the remains of those who were stolen from their homelands are respectfully repatriated.”
Britain has strict guidelines on the storage and treatment of human remains, but their sale is permitted provided they are obtained legally.
Saleroom, an online auction site, removed the skulls from sale after being contacted by The Guardian. Its website states that human remains are prohibited from sale.
A spokesperson said: “These items are legal for sale in the UK and are of archaeological and anthropological interest.
“However, after discussion with the auctioneer we have removed the items while we consider our position and wording of our policy.”
Prof. Dan Hicks, Pitt Rivers Museum’s curator of world archaeology, said: “This sale from a legacy colonial collection that was sold off in the last century shines a light on ethical standards in the art and antiquities market.
“I hope that this will inspire a new national conversation about the legality of selling human remains.”
Some of the skulls in the auction had been marked with phrenological measurements by the original collector, he said.
“The measurements of heads in order to try to define human types or racial type was something that Pitt Rivers was continuing to do with archaeological human remains in order to try to add to his interpretations of the past.”
UK students launch fresh wave of pro-Palestine protests
- Activists plan rallies and encampments on campuses across the country
- They aim to persuade universities to divest from arms companies supplying weapons to Israel
LONDON: Students in the UK are launching a fresh round of demonstrations against the war in Gaza.
The latest protests were expected to begin on Wednesday on the campuses of at least six British universities, including Sheffield, Bristol, Leeds and Newcastle, The Guardian newspaper reported. They come at a time when authorities in the US are violently cracking down on similar demonstrations.
The British students are demanding that their universities divest from arms companies that supply weapons to Israel, and in some cases that they sever all academic ties with Israeli institutions.
In Britain, regular mass public marches in London and other cities have attracted most of the attention surrounding the pro-Palestinian protest movement, with little attention so far paid to demonstrations at universities.
However, recent events in the US, including massive protests at Columbia University in New York, have encouraged student demonstrators in Britain to ramp up their efforts.
A coalition of “staff, students and alumni” at Sheffield and Sheffield Hallam universities have established an encampment in solidarity with the Palestinian people, as part of a group calling itself the Sheffield Campus Coalition for Palestine. This week, students are expected to stage walkouts from lectures and take part in a demonstration in Sheffield.
Similar activities are expected in Newcastle, organized by a group called Newcastle Apartheid off Campus. More than 40 students at the city’s university reportedly have set up an encampment on campus and planned to stage a rally on Wednesday. Organizers said students are protesting against Newcastle University’s partnership with defense firm Leonardo SpA, which produces the laser guidance system for the F-35 jets that have been used by the Israeli military in Gaza.
They added: “Although the student union has passed motions with 95 percent of people in favor of calling for the university to end its ties with Leonardo, and multiple ‘Leonardo off Campus’ protests on its campus, it is clear that the university has not listened to students’ concerns.”
Students in Leeds and Bristol are involved in similar activities, including rallies and encampments.
A spokesperson for Universities UK, which represents 142 academic institutions, said: “Universities are monitoring the latest news on campus protests in the US and Canada.
“As with any high-profile issue, universities work hard to strike the right balance between ensuring the safety of all students and staff, including preventing harassment, and supporting lawful free speech on campus. We continue to meet regularly to discuss the latest position with university leaders.”
