Toothache? Scientists find Neanderthals used antibiotics and aspirin too

This photo provided by Paleoanthropology Group MNCN-CSIC shows an El Sidron upper jaw. This individual was eating poplar, a source of aspirin, and had also consumed molded vegetation including Penicillium fungus, source of a natural antibiotic. (AP)
Updated 09 March 2017
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Toothache? Scientists find Neanderthals used antibiotics and aspirin too

PARIS: Nearly 50,000 years before the invention of penicillin, a young Neanderthal tormented by a dental abscess ate greenery containing a natural antibiotic and pain killer, analysis of his teeth revealed Wednesday.
The male, who lived in El Sidron in what is now Spain, ate an antibiotic fungus called Penicillium and chewed on bits of poplar tree containing salicylic acid — the active ingredient of modern-day aspirin, researchers said.
The youngster’s fossilized jawbone reveals the ravages of an abscess, and his dental plaque contained the remnants of an intestinal parasite that causes acute diarrhea, “so clearly he was quite sick,” they wrote in the journal Nature.
“Apparently, Neanderthals possessed a good knowledge of medicinal plants and their various anti-inflammatory and pain-relieving properties, and seem to be self-medicating,” said study co-author Alan Cooper of the University of Adelaide’s Australian Center for Ancient DNA (ACAD).
“Certainly, our findings contrast markedly with the rather simplistic view of our ancient relatives in popular imagination,” he added.
The study is the latest to recast our long-extinct cousins, long thought of as thick-skulled and slow-witted, in a more positive light.
Other recent findings have started to paint a picture of Neanderthals as sophisticated beings who made cave art, took care of the elderly, buried their dead and may have been the first jewelers — though they were probably also cannibals.
In 2012, a study in the journal Naturwissenschaften said Neanderthals appeared to have used medicinal herbs such as yarrow and chamomile.
Neanderthals lived in parts of Europe, Central Asia and the Middle East for up to 300,000 years but appear to have vanished some 40,000 years ago.
This coincided more or less with the arrival of homo sapiens out of Africa, where modern humans emerged some 200,000 years ago.

Neanderthals and homo sapiens interbred, leaving a small contribution of less than two percent to the DNA of all humans except for people from Africa, where Neanderthals never lived.
For the latest study, an international team did a genetic analysis of DNA trapped in the dental plaque of four Neanderthals — two from Spy Cave in Belgium and two from El Sidron.
Calcified plaque preserves the DNA of microorganisms that lived in the mouth, windpipe and stomach, as well as bits of food stuck between teeth — which can later reveal what a creature ate and what its state of health was.
From the oldest plaque ever to be genetically analyzed, the team concluded the Belgian Neanderthals ate a diet of woolly rhino, wild sheep and mushrooms, living a hunter-gatherer lifestyle.
“Those from El Sidron Cave, on the other hand, showed no evidence for meat consumption, but appeared instead to have a largely vegetarian diet comprising pine nuts, moss, mushrooms and tree bark,” Cooper said in a statement.
El Sidron at the time was in a densely forested environment, added the study’s lead author Laura Weyrich, also from ACAD.
“In contrast, the Spy Neanderthals were living in a steppe-like environment, so it’s easy to picture large, beastly animals wandering around as a major source of food,” she told AFP.
The sick Spanish Neanderthal was the only one with traces of poplar or Penicillium in his dental plaque.
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Apple to update EU browser options, make more apps deletable

Updated 22 August 2024
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Apple to update EU browser options, make more apps deletable

  • iPhone maker came under pressure from regulators to make changes after the EU’s sweeping Digital Markets Act took effect on March 7
  • Apple users will be able to select a default browser directly from the choice screen after going through a mandatory list of options

STOCKHOLM: Apple will change how users choose browser options in the European Union, add a dedicated section for changing default apps, and make more apps deletable, the company said on Thursday.
The iPhone maker came under pressure from regulators to make changes after the EU’s sweeping Digital Markets Act took effect on March 7, forcing big tech companies to offer mobile users the ability to select from a list of available web browsers on a “choice screen.”
The new rules require mobile software makers to show the choice screen where users can select a browser, search engine and virtual assistant as they set up their phones, which earlier came with preferred options from Apple and Google.
In an update later this year, Apple users will be able to select a default browser directly from the choice screen after going through a mandatory list of options.
A randomly ordered list of 12 browsers per EU country will be shown to the user with short descriptions, and the chosen one will be automatically downloaded, Apple said. The choice screen will also be available on iPads through an update later this year.
Apple released a previous update in response to the new rules in March, but browser companies criticized the design of its choice screen, and the Commission opened an investigation on March 25 saying it suspected that the measures fell short of effective compliance.
The company said it has been in dialogue with the European Commission and believes the new changes will address regulators’ concerns.
It also plans to introduce a dedicated area for default apps where a user will be able to set defaults for messaging, phone calls, spam filters, password managers and keyboards.
Users will also be able to delete certain Apple-made apps such as App Store, Messages, Camera, Photos and Safari. Only Settings and Phone apps would not be deletable.