GENEVA: An international team of scientists say they have identified a compound that can fight coronaviruses, responsible for the SARS and MERS outbreaks, which currently have no cure.
Coronaviruses affected the upper and lower respiratory tracts in humans.
They are the reason for up to a third of common colds.
A more severe strain of the virus, thought to have come from bats, triggered the global SARS (Severe Acute Respiratory Syndrome) epidemic in 2002 that killed nearly 800 people.
The Middle East Respiratory Syndrome (MERS) is a new strain discovered in Saudi Arabia in 2012 and thought to have originated in camels. More deadly but less contageous, it has so far killed 193 people across 636 confirmed cases.
But now a team of scientists led by Edward Trybala from the University of Gothenburg in Sweden, and Volker Thiel from the University of Bern have discovered a compound called K22, which appears to block the ability of the virus to spread in humans.
They first noticed that K22 was able to combat a weak form of coronavirus that causes mild cold-like symptoms, and went on to show that it can fight more serious strains, including SARS and MERS.
In an article for specialist journal "PLOS Pathogens", the scientists explained that the virus reproduces in the cells that line the human respiratory system.
The virus takes over the membranes that separate different parts of human cells, reshaping them into a sort of armour around itself in order to start its production cycle.
But K22 acts at an early stage in this process, preventing the virus from taking control of the cell membranes.
"The results confirm that the use of the membrane of the host cell is a crucial step in the life-cycle of the virus," the researchers wrote.
Their work shows that "the process is highly sensitive and can be influenced by anti-viral medications."
They said the recent SARS epidemic and MERS outbreak mean there should be urgent investment in testing K22 outside the laboratory and developing medicines.
Earlier this month, experts gathered in Geneva by the World Health Organisation confirmed that MERS was spreading but had yet to reach the level of global emergency.
Most of the MERS cases and deaths so far have been in Saudi Arabia, but the virus has been imported to more than a dozen other countries.
All of those cases have involved people who became ill while in the Middle East.
Iran registered its first death from MERS on Thursday, and has registered six cases of the infection.
Scientists find compound to fight virus behind MERS and SARS
Scientists find compound to fight virus behind MERS and SARS
Where We Are Going Today: Don Ruben’s Mexican Restaurant
- For something more indulgent, the shrimp fajitas arrived sizzling at the table, filling the air with the aroma of garlic and spices
Tucked inside the Diplomatic Quarter, Don Ruben’s Mexican Restaurant feels like a small slice of Mexico in the Saudi capital.
The moment you arrive, the atmosphere shifts — colorful decor abounds, with upbeat Latin music. The smell of grilled tortillas drifting from the kitchen creates a casual, welcoming space that invites diners to settle in and stay.
The restaurant has built a reputation as one of Riyadh’s go-to spots for Mexican comfort food, serving generous plates of tacos, burritos and fajitas in a lively, easygoing setting.
The atmosphere is relaxed and friendly, making it a popular choice for families and groups of friends looking for a fun meal rather than a formal dining experience.
On my visit, the table was quickly filled with some of the restaurant’s favorites. The guacamole, served fresh and bright with lime and cilantro, was a simple but satisfying start. Paired with warm tortilla chips, it was the perfect way to ease into the meal.
The real highlight, however, was the tacos. The beef tacos were packed with flavor, with tender meat tucked into soft tortillas and topped with fresh onions and cilantro.
At around SR35 ($9) to SR45 for a plate, depending on the filling, it felt reasonably priced for the size of the portion.
Another standout was the chicken burrito, a hearty dish loaded with rice, beans and grilled chicken, wrapped in a soft tortilla and served with fries. It was large enough to share — though you may not want to.
For something more indulgent, the shrimp fajitas arrived sizzling at the table, filling the air with the aroma of garlic and spices. Priced at about SR65, it is a satisfying dish that balances bold flavor with generous portions.
Service during my visit was friendly and relaxed, adding to the laid-back vibe that makes the restaurant easy to enjoy with friends or family.
If there is one negative, it is that the restaurant can get quite busy during peak hours, especially on weekends, which sometimes means waiting a little longer for a table and for the food to arrive.
Still, Don Ruben’s delivers exactly what it promises: bold flavors, satisfying portions and a cheerful atmosphere. It remains one of Riyadh’s most reliable spots for tacos, burritos and a casual taste of Latin America.
