KARACHI: A 23-year-old man died in Pakistan’s southern port city of Karachi this week after contracting Naegleria fowleri, the Sindh Health Department said on Wednesday, marking the second death of the year from the deadly brain-eating amoeba.
Naegleria fowleri, commonly known as the brain-eating amoeba, has a fatality rate of over 98 percent. It is transmitted when contaminated water enters the body through the nose and cannot be spread from person to person.
Pakistan has witnessed a rise in Naegleria fowleri cases in recent years, with more than 100 reported deaths since the first confirmed infection in 2008. Five fatalities were recorded in 2024 alone.
In the latest case the deceased, a resident of Karachi’s Orangi Town area, was hospitalized on May 30 after suffering from symptoms on May 28. He died on June 3 after the presence of Naegleria fowleri was confirmed in the patient on June 1.
“Upon investigation, it was noted that the patient had not participated in any water-related activities,” the Sindh Health Department said. “His only exposure was regular use of water at home and use of water at a nearby local mosque to perform ablution.”
Symptoms of Naegleria fowleri infection include severe headache, altered sense of taste, high fever, sensitivity to light, nausea and vomiting. Death typically occurs within five to seven days of infection.
The health department confirmed this was the second death in Pakistan from Naegleria fowleri in 2025. The first death was reported in March when a 36-year-old woman died from the same disease. She was also a resident of Karachi.
A 2021 study by the Sindh Health Department found that 95 percent of water samples in Karachi, Sindh’s provincial capital, were unfit for human consumption.
Experts say the contamination leads to the spreading of the brain-eating amoeba among the city’s residents.
