Pakistan requests WHO for Mpox vaccine for critical patient with HIV infection

Medical staff members prepare rooms in an isolation ward at the Pakistan Institute of Medical Sciences hospital in Islamabad on January 31, 2020. (AFP/File)
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Updated 10 November 2023
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Pakistan requests WHO for Mpox vaccine for critical patient with HIV infection

  • The patient is treated at a public hospital where he is struggling due to the nonavailability of required vaccine
  • A recent research study reveals the mortality rate in Mpox patients with advanced HIV infection is 15 percent

ISLAMABAD: Pakistan has requested the World Health Organization (WHO) to provide monkeypox vaccine for a 40-year-old male patient who is also HIV positive and admitted in a public hospital in Islamabad in critical condition, an official revealed on Friday.

Monkeypox, or Mpox, is a zoonotic infection which can spread from animals to humans. The viral disease can also be contracted from one person to another and cause high fever and body pains.

Pakistan confirmed its first three cases of Mpox in April, with all three of the affected individuals arriving from abroad. They all later tested negative for the disease.

Officials at the public hospital in Islamabad are keeping the identity of the 40-year-old Mpox patient from Khyber Pakhtunkhwa province secret since he is also HIV positive. In Pakistan, talking about HIV/AIDS is considered taboo and can lead to discrimination and social stigma.

“This patient is admitted in the hospital for over a month now, and he is in critical condition,” Dr. Nasim Akhtar, head of infectious diseases at the Pakistan Institute of Medical Sciences (PIMS) in Islamabad, told Arab News. “He is struggling for his life as the required drug is not available to treat him.”

Akhtar said the authorities had written to WHO officials for the antiviral medicines for the patient since it was “a unique case in a sense that he is infected with both Mpox and HIV at the same time.”

A recent research study revealed that Mpox can have a devasting impact on people with advanced cases of HIV, leading to “15 percent mortality in individuals with advanced HIV related disease characterized by CD4 [white blood cell] cell counts below 200 cells per mm3.” The mortality rate of the disease in normal patients was close to 0.2 percent globally.

The PIMS doctor said the patient’s health was deteriorating with each passing day, adding his chances of survival could increase if the hospital would get the required vaccine at the earliest.

“It has been over three weeks now since we wrote to the WHO for the vaccine, but we have not received it so far,” she continued, adding that all the paperwork required for to get the antiviral drug had been completed, but the international agency responsible for public health had yet to deliver it.

The WHO office in Pakistan did not respond to Arab News queries seeking an update on Islamabad’s request for the vaccine.

The goal of treating Mpox is to take care of the rash caused by the disease, manage pain and prevent related complications. Early and supportive care is important to help manage symptoms and avoid further problems, the WHO said in its advisory.

“Persons who have Mpox should be cared for away from other people,” it added. “Several antivirals, such as tecovirimat, originally developed to treat smallpox have been used to treat Mpox and further studies are underway.”

The most common symptoms of Mpox include fever, headache, muscle aches, back pain, low energy and swollen lymph nodes, followed or accompanied by the development of a rash which may last for two to three weeks, according to the WHO.

Dr. Abdul Ghafoor Shoro, general secretary of the Pakistan Medical Association, said the HIV infection could destroy the patient’s immune system, adding his recovery would only be possible through timely and effective treatment.

“The government should take up the issue of Mpox vaccine acquisition at the highest level in WHO as this is a matter of a human life,” he told Arab News. “Just writing a letter to WHO for the vaccine does not absolve them of their responsibility.”


Islamabad, UAE to sign ‘Pre-Immigration Clearance’ pact easing travel for Pakistani passengers

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Islamabad, UAE to sign ‘Pre-Immigration Clearance’ pact easing travel for Pakistani passengers

  • UAE DG Customs Abdullah Bin Lahej Al Falasi meets Pakistan’s Interior Minister Mohsin Naqvi to discuss simplifying immigration procedures
  • Under the new system, immigration and relevant clearance of passengers will take place within Pakistan itself, says Pakistani interior ministry 

ISLAMABAD: Islamabad and the UAE will sign a formal “Pre-Immigration Clearance” pact allowing Pakistani passengers traveling to the Gulf country to avoid lengthy procedures at airports, the Pakistani interior ministry said on Monday. 

The ministry’s statement followed a meeting between Pakistan’s Interior Minister Mohsin Naqvi and a UAE delegation led by its Director General Customs Ahmed Abdullah Bin Lahej Al Falasi. The two sides held detailed discussions on Pakistan-UAE ties, mutual cooperation and simplifying immigration processes for travelers, the interior ministry said. 

‎“During the meeting, both sides agreed that a formal pact on ‘Pre-Immigration Clearance’ between Pakistan and the UAE would be signed,” the statement said. “The system will initially be launched on a pilot basis, with Karachi selected as the first location.”

Naqvi said that as per the under the new system, immigration and relevant clearance of passengers traveling to the UAE will take place in Pakistan. After its implementation, passengers arriving in the UAE will not be required to undergo lengthy immigration procedures and will be able to exit the airport directly as “domestic passengers,” the ministry said. 

The minister said this initiative will make travel easier, save time and enhance the overall experience of passengers. 

“The UAE delegation termed the move beneficial for the people of both countries and expressed readiness for cooperation,” the statement said. 

The Pakistani interior ministry did not say when the pact would be signed. However, it said both sides decided that relevant authorities would continue coordination to finalize the administrative and technical framework of the pilot project. 

Upon successful implementation, the system would be gradually expanded to more destinations, it said. 

Pakistan has a similar arrangement with Saudi Arabia under the Kingdom’s Makkah Route Initiative. The scheme streamlines immigration processes by enabling Hajj pilgrims to complete official travel formalities at their departure airports. 

This saves pilgrims several hours upon arrival in the Kingdom, as they can simply enter the country without having to go through immigration again.