Pakistani startup using AI for breast cancer detection eyes FDA approval, Middle East expansion

The image shows people working at Pakistani startup Xylexa office in Islamabad, Pakistan, on November 29, 2022. (AN Photo)
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Updated 05 December 2022
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Pakistani startup using AI for breast cancer detection eyes FDA approval, Middle East expansion

  • Xylexa’s technology has gone through clinical trials at several medical facilities in Pakistan and abroad
  • Startup recently got its first contract in Lebanon and is now looking into opportunities in UAE, Saudi Arabia

ISLAMABAD: An award-winning Pakistani startup that uses artificial intelligence and cloud-based tools for breast cancer detection is now working on getting approval from the US Food and Drug Administration (FDA) and pursuing expansion into Arab countries, the founders of the firm said this week.

According to the International Agency for Research on Cancer (IARC), Pakistan has the highest breast cancer rate in Asia, with one out of nine Pakistani women now facing a lifetime risk of the disease. The country also has one of the highest breast cancer mortality rates globally.

Known as Xylexa, the Islamabad-based startup was founded in 2018 by entrepreneurs Shahid Abbasi, Shahrukh Babar, and Neda Nehal who met each other by chance at an IT industry event in 2017.

The three individuals thus embarked on a mission to fight the disease by empowering radiologists — medical doctors that specialize in diagnosing and treating injuries and diseases using medical imaging procedures — with tools and technologies that would render improved clinical outcomes for the patients.

“We have developed a decision support program for interpretation of medical images which use cutting edge technologies like artificial intelligence, computer vision, and deep learning that would help radiologists attain better clinical insights,” Abbasi, the co-founder of the startup, told Arab News in an interview in Islamabad this week.




Xylexa team poses for a picture after receiving the Pasha Technology of the Year Award in Islamabad, Pakistan on September 7, 2018. (Photo courtesy: Xylexa)

The inspiration to do something for breast cancer patients came when a close relative was diagnosed with the disease at a very late stage, he said.

“We got together as a group and decided to do something about it and use technology as a medium to save more lives,” Abbasi added.

The first set of algorithms that Xylexa developed was for the detection of breast cancer using mammography, he said, and its clinical evaluation was successfully concluded after the hard work of three and half years.

“We are not just stopping at mammography but now we are focused on developing support for 14 different diseases that require chest x-rays and have also developed algorithms for protection of blockages within the arterial system,” Abbasi said.




 Lieutenant General Nigar Johar, Surgeon General Pakistan Army (2nd right) is visiting Xylexa office in Islamabad, Pakistan on September 13, 2021. (Photo courtesy: Xylexa)

The entrepreneur said his company’s product delivered results with an up to a 95 percent accuracy ratio, thus giving 24 percent better results than traditional radiology examination.

“If you look at the market data available for the accuracy of radiologists’ readings, it ranges anywhere between 71 percent to 82 percent. On the other hand, the accuracy rates of three algorithms that we have developed for mammography, chest x-ray, and peripheral artery disease detection ranges anywhere between 89 percent to 95 percent,” he added.

After developing an AI and cloud-based platform to provide support for breast cancer detection, Xylexa put it through clinical validation at various medical facilities in Pakistan and abroad.

According to StartUs Insights, an Austrian company that has evaluated almost 359 companies across the globe using artificial intelligence in health care, Xylexa was among the top five performers in this domain.

Babar, another co-founder of the startup, said the team was now applying for approval from the Food and Drug Administration (FDA) in the United States after completing clinical trials.

“We ran a trial in Pakistan with Fouji Foundation Hospital, Islamabad Diagnostic Center, and Epiphany Labs,” he said, adding that the startup was also expanding to Arab countries.

“Recently, we got our first contract in Lebanon and we are looking at a few opportunities in Saudi Arabia too. We have already carried out trials with the King Fahad Hospital in the Kingdom and now are in talks with a few potential partners in Dubai as well.”

Babar said breast cancer could be successfully cured with early detection.

“If breast cancer is diagnosed at an early stage, chances of survival are 90 percent,” he said. “If it is diagnosed at a later stage, then chances of survival remain 25 percent or even less.”


Pakistan joins regional talks on Afghanistan in Iran as Kabul stays away

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Pakistan joins regional talks on Afghanistan in Iran as Kabul stays away

  • China, Pakistan, Pakistan, Tajikistan, Uzbekistan, Turkmenistan all joined talks organized by Iran, as did Russia
  • Afghanistan was invited but decided not to attend, Taliban-led government was tight-lipped on the reasons

TEHRAN, Iran: Afghanistan’s neighbors met in Iran and agreed to deepen regional coordination to address political, economic and security challenges, as well as calling for sanctions on Afghanistan to be lifted. 

The only absent party? Afghanistan itself.

China, Pakistan, Pakistan, Tajikistan, Uzbekistan and Turkmenistan all joined the talks organized by Iran, as did Russia, according to a statement released after the meeting on Sunday.

Afghanistan was invited but decided not to attend. Its Taliban-led government was tight-lipped on the reasons, with the foreign ministry saying only that it would not participate because Afghanistan “currently maintains active engagement with regional countries through existing regional organizations and formats, and has made good progress in this regard.”

The statement from the talks in Iran stressed the importance of maintaining economic and trade ties with Afghanistan to improve living conditions and called for the country’s integration into regional political and economic processes.

The Taliban were isolated after they retook power in Afghanistan in August 2021, but in the past year, they have developed diplomatic ties. They now raise several billion dollars every year in tax revenues to keep the lights on.

However, Afghanistan is still struggling economically. Millions rely on aid for survival, and the struggling economy has been further impacted by the international community not recognizing the Taliban government’s seizure of power in the wake of the chaotic withdrawal of US-led troops in 2021. Natural disasters and the flow of Afghans fleeing Pakistan under pressure to return home have underlined Afghanistan’s reliance on foreign aid to meet essential needs.

The countries at the talks also voiced security concerns and pledged cooperation in combating terrorism, drug trafficking and human smuggling, while opposing any foreign military presence in Afghanistan. They underscored the responsibility of the international community to lift sanctions and release Afghanistan’s frozen assets, and urged international organizations to support the dignified return of Afghan refugees from neighboring countries.

The participants backed efforts to reduce tensions between Afghanistan and Pakistan, which have been particularly strained, with border clashes between the two sides killing dozens of civilians, soldiers and suspected militants and wounding hundreds more.

The violence followed explosions in Kabul on Oct. 9 that Afghan authorities blamed on Pakistan. A Qatar-mediated ceasefire has largely held since October, although there have been limited border clashes. The two sides failed to reach an overall agreement in November despite three rounds of peace talks.

Asif Durrani, Pakistan’s former special representative for Afghanistan, said the Taliban government’s decision to skip the meeting reflected a “lack of political maturity.” 

Writing on X, Durrani said the move reinforced concerns that the Taliban were unwilling to negotiate, instead adopting an “I don’t accept” stance that he said would do little to resolve serious regional problems.

Mohammad Sadiq, the current Pakistani special representative for Afghanistan who attended the talks, wrote on X that the Afghan people had already suffered enough and deserved better.

Only an Afghanistan that does not harbor militants would inspire confidence among neighboring and regional countries to engage meaningfully with Kabul and help unlock the country’s economic and connectivity potential, he wrote.

Participants agreed to hold the next meeting of foreign ministers of Afghanistan’s neighboring countries as soon as possible in Ashgabat, Turkmenistan, and welcomed Pakistan’s offer to host the next round of special envoys’ talks in Islamabad in March.

Iran’s foreign ministry spokesman, Esmail Baghaei, on Sunday said that the meeting had not been held for about two years and marked the first such gathering attended by special envoys on Afghanistan from neighboring countries as well as Russia. Russia and Uzbekistan sent the special envoys of their presidents, while Pakistan was represented by a delegate from the prime minister’s office.

Landlocked Afghanistan is sandwiched between the Middle East, Central Asia, and South Asia, making it strategically located for energy-rich and energy-hungry nations.