Pakistani startup using AI for breast cancer detection eyes FDA approval, Middle East expansion

The image shows people working at Pakistani startup Xylexa office in Islamabad, Pakistan, on November 29, 2022. (AN Photo)
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Updated 05 December 2022
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Pakistani startup using AI for breast cancer detection eyes FDA approval, Middle East expansion

  • Xylexa’s technology has gone through clinical trials at several medical facilities in Pakistan and abroad
  • Startup recently got its first contract in Lebanon and is now looking into opportunities in UAE, Saudi Arabia

ISLAMABAD: An award-winning Pakistani startup that uses artificial intelligence and cloud-based tools for breast cancer detection is now working on getting approval from the US Food and Drug Administration (FDA) and pursuing expansion into Arab countries, the founders of the firm said this week.

According to the International Agency for Research on Cancer (IARC), Pakistan has the highest breast cancer rate in Asia, with one out of nine Pakistani women now facing a lifetime risk of the disease. The country also has one of the highest breast cancer mortality rates globally.

Known as Xylexa, the Islamabad-based startup was founded in 2018 by entrepreneurs Shahid Abbasi, Shahrukh Babar, and Neda Nehal who met each other by chance at an IT industry event in 2017.

The three individuals thus embarked on a mission to fight the disease by empowering radiologists — medical doctors that specialize in diagnosing and treating injuries and diseases using medical imaging procedures — with tools and technologies that would render improved clinical outcomes for the patients.

“We have developed a decision support program for interpretation of medical images which use cutting edge technologies like artificial intelligence, computer vision, and deep learning that would help radiologists attain better clinical insights,” Abbasi, the co-founder of the startup, told Arab News in an interview in Islamabad this week.




Xylexa team poses for a picture after receiving the Pasha Technology of the Year Award in Islamabad, Pakistan on September 7, 2018. (Photo courtesy: Xylexa)

The inspiration to do something for breast cancer patients came when a close relative was diagnosed with the disease at a very late stage, he said.

“We got together as a group and decided to do something about it and use technology as a medium to save more lives,” Abbasi added.

The first set of algorithms that Xylexa developed was for the detection of breast cancer using mammography, he said, and its clinical evaluation was successfully concluded after the hard work of three and half years.

“We are not just stopping at mammography but now we are focused on developing support for 14 different diseases that require chest x-rays and have also developed algorithms for protection of blockages within the arterial system,” Abbasi said.




 Lieutenant General Nigar Johar, Surgeon General Pakistan Army (2nd right) is visiting Xylexa office in Islamabad, Pakistan on September 13, 2021. (Photo courtesy: Xylexa)

The entrepreneur said his company’s product delivered results with an up to a 95 percent accuracy ratio, thus giving 24 percent better results than traditional radiology examination.

“If you look at the market data available for the accuracy of radiologists’ readings, it ranges anywhere between 71 percent to 82 percent. On the other hand, the accuracy rates of three algorithms that we have developed for mammography, chest x-ray, and peripheral artery disease detection ranges anywhere between 89 percent to 95 percent,” he added.

After developing an AI and cloud-based platform to provide support for breast cancer detection, Xylexa put it through clinical validation at various medical facilities in Pakistan and abroad.

According to StartUs Insights, an Austrian company that has evaluated almost 359 companies across the globe using artificial intelligence in health care, Xylexa was among the top five performers in this domain.

Babar, another co-founder of the startup, said the team was now applying for approval from the Food and Drug Administration (FDA) in the United States after completing clinical trials.

“We ran a trial in Pakistan with Fouji Foundation Hospital, Islamabad Diagnostic Center, and Epiphany Labs,” he said, adding that the startup was also expanding to Arab countries.

“Recently, we got our first contract in Lebanon and we are looking at a few opportunities in Saudi Arabia too. We have already carried out trials with the King Fahad Hospital in the Kingdom and now are in talks with a few potential partners in Dubai as well.”

Babar said breast cancer could be successfully cured with early detection.

“If breast cancer is diagnosed at an early stage, chances of survival are 90 percent,” he said. “If it is diagnosed at a later stage, then chances of survival remain 25 percent or even less.”


Pakistani religious party vows to continue sit-in in Rawalpindi despite government’s offer for talks

Updated 7 sec ago
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Pakistani religious party vows to continue sit-in in Rawalpindi despite government’s offer for talks

  • Jamaat-e-Islami supporters have been holding a sit-in at a key intersection in Rawalpindi since Friday
  • The party wants the government to address cost-of-living crisis, remove additional taxes in the budget

ISLAMABAD: Jamat-e-Islami (JI), a Pakistani religio-political party, on Saturday vowed to continue its sit-in in Rawalpindi against the rising cost of living and additional taxes imposed in the latest budget, despite the government forming a negotiation committee for talks with the protesters.
The JI, led by Hafiz Naeem-ur-Rehman, announced the sit-in in Islamabad to call for a reduction in power tariff amid soaring inflation and to review Pakistan’s agreements with independent power producers (IPPs).
The party’s caravans entered the capital from different directions as the district administration closed the capital’s Red Zone, which houses top government offices and the diplomatic enclave, with shipping containers and roads leading to parliament.
“Our dharna will continue as long as the government accepts our demands for a significant reduction in inflation and electricity prices,” Aamir Baloch, a JI spokesperson, told Arab News.
“The party chief Hafiz Naeem-ur-Rehman will be announcing a fresh strategy for the protests, dharna and engagement with the government today afternoon.”
The government has formed a three-member committee, which includes Information Minister Attaullah Tarar and two senior members of the ruling Pakistan Muslim League-Nawaz (PML-N) party, to hold talks with the JI leadership.
“We are ready for negotiations, but don’t disrupt public life,” Tarar said at a news conference on Friday. “The government’s three-member committee will talk to you. Amir Muqam, Tariq Fazal Chaudhry and I will negotiate with you. Whenever you express willingness, we are ready for the negotiations.”
But Baloch said the party would continue its protest and JI chief Rehman would join the sit-in at Zero Point — a major intersection in the city where various key roads and highways connect with each other — on Saturday.
He said thousands of JI workers had already reached the area, despite the government’s “brutalities.”
“The police have arrested dozens of our peaceful workers from D-Chowk,” he said, referring to a key spot close to the parliament building in Islamabad.
“The government wants to incite the peaceful protesters through such strong-arm tactics. It will be responsible for any law-and-order situation, if our workers are not released immediately.”
Police in the capital have deployed additional contingents, including personnel with riot gears, to prevent any untoward incident.
The Rawalpindi-Islamabad Expressway has also been closed with shipping containers near the Zero Point bridge, where the JI protesters have gathered.
Baloch said the party leadership would announce their future course of action after reaching Zero Point.
“One thing is for sure,” he said. “We are here to stay and will definitely stage a sit-in to press the government to meet our legitimate demands regarding inflation and taxes.”


Protesters in northwest Pakistan end weeklong sit-in after CM assures no military operation being launched

Updated 38 min 30 sec ago
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Protesters in northwest Pakistan end weeklong sit-in after CM assures no military operation being launched

  • Pakistan’s government last month announced a new campaign to counter a fresh surge in militancy in areas along the border with Afghanistan
  • The announcement raised fears among locals as past operations displaced hundreds of thousands of people and destroyed livelihoods in region

PESHAWAR: Thousands of protesters, who had been staging a sit-in in Pakistan’s Bannu district for a week, on Friday called off their protest after Chief Minister Ali Amin Gandapur assured them that no military operation was being launched in the northwestern Khyber Pakhtunkhwa (KP) province.
Pakistan’s government last month announced a new campaign to counter a fresh surge in militancy in areas along the border with Afghanistan. Major opposition parties opposed the operation and in Bannu — where eight soldiers were killed in a suicide bombing last week — thousands held rallies to call for peace and security.
One of the key demands of the protesters in Bannu was for the government to not launch any new military operation in the province. They demanded that a spike in militant attacks in the region be tackled by empowering and better equipping civilian agencies like the police and the counter-terrorism department (CTD).
On Friday, CM Gandapur traveled to Bannu where he spoke to the protesters and announced at a rally that all their demands had been accepted in letter and spirit, lauding local elders for helping avert violence when two protesters were killed after gunfire triggered a stampede at the rally on June 19.
“I have a signed copy [of the demands]. It has been done the way you [protesters] wanted,” he told the gathering. “I’m the owner of this soil and land, no one can oppress me or coerce me. As chief minister, I declare that there will be no operation in the province.”
The announcement came a day after the provincial apex committee, which comprises civilian leaders and military commanders in the province, met to discuss the situation in Bannu. The KP government later clarified that police and the CTD would be tasked to take action against militants amid a surge in violence in the area.
The resentment for military operation stems from past displacement of hundreds of thousands of people and destruction of countless homes and businesses in successive military campaigns in KP that began in 2014. But Pakistani military spokesman Lt Gen Ahmed Sharif Chaudhry dispelled the fears this week, saying the newly proposed Azm-e-Istehkam campaign was not meant to be a full-scale military operation.
“We have offered sacrifices for our homeland and stood loyal to the country and its people. We left our homes and became nomads for our land and for the sake of peace,” Gandapur said. “We will offer sacrifices again but we will make the decisions ourselves and will not allow anyone to impose their decisions.”
The chief minister appreciated police for taking swift action against illegal armed groups in Bannu.
Provincial Minister for Public Health Engineering Pakhtunyar Khan, who hails from Bannu, said the people of the region had experienced “unspeakable hardships” for the sake of peace.
“We want peace for the entire province and we will not back down from this demand,” Khan said at the rally.
On Thursday, the apex committee said the judiciary would be requested to hold an inquiry into the Bannu shooting incident, a demand that had been put forward by protesters and Pakistan’s opposition alliance.
“Meanwhile, the government will hold its own inquiry and identify the persons responsible,” it said in a statement.


Pakistan plans to launch panda bonds, seeks cooperation of Chinese capital market investors

Updated 20 min 16 sec ago
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Pakistan plans to launch panda bonds, seeks cooperation of Chinese capital market investors

  • The bonds are denominated in China’s currency and will provide Pakistan access to Chinese capital markets
  • The finance minister also discusses the next CPEC stage, expected to emphasize business-to-business ties

ISLAMABAD: Federal Minister for Finance and Revenue Muhammad Aurangzeb briefed Governor of People’s Bank of China (PBoC) Pan Gongsheng on Pakistan’s plan to launch panda bonds during a meeting in Beijing on Friday in which they discussed a wide range of economic issues.
Panda bonds are sold in China’s domestic market and are denominated in its currency, though they are issued by non-Chinese entities. Pakistan plans to issue these bonds to diversify its funding sources and strengthen its foreign exchange reserves by attracting Chinese investors.
According to local media reports, the initial issuance is expected to raise between $250 million and $300 million, helping Pakistan improve its financial stability amid economic challenges like high inflation and declining forex reserves.
The minister spoke about the government’s economic policy during the meeting in which reprentatives of other financial institutions were also present.
“Underlining Pakistan’s plan to launch panda bonds, Minister for Finance briefed PBoC and other Financial Institutions about the steps taken so far and sought cooperation of the Chinese institutional investors in the capital market to seek benefit from the pro-business policies of the new [Pakistani] Government,” said a statement issued by the finance division after the meeting.
The Pakistani official also highlighted his country’s improving macroeconomic indicators, reforms in tax collection and energy sector and privatization of loss-making state-owned enterprises.
He applauded Chinese President Xi Jinping’s Belt and Road Initiative while reviewing the progress of its flagship China-Pakistan Economic Corridor (CPEC) project.
The minister noted the next phase of CPEC would focus on strengthening business-to-business cooperation, with private sector playing the central role in the development and economic growth.
He arrived in China on Thursday to open talks on power sector structural reforms suggested by the International Monetary Fund, two government sources quoted by Reuters.
Aurangzeb is also accompanied by Pakistan’s Power Minster Awais Ahmed Khan Leghari.
According to Reuters, both officials are expected to take up several proposals with the Chinese side, including reprofiling of nearly $15 billion energy sector debt.


Pakistani craftsman strives to preserve antiques in a dying industry

Updated 27 July 2024
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Pakistani craftsman strives to preserve antiques in a dying industry

  • Based in Rawalpindi’s Bhabra Bazaar, Mohammad Shakeel Abbasi has restored centuries-old bugles, decorative dishes, jars, vases and teapots 
  • Artefacts at Abbasi’s shop sell for anywhere between $40 to $1,000, many collectors place orders after coming across antiques online

RAWALPINDI: Antiquarian Mohammad Shakeel Abbasi pulled open the shutter of his shop in the Pakistani city of Rawalpindi to reveal a small space choke-full of bugles, decorative dishes, jars, vases, teapots, bowls and plates inscribed with ancient motifs.
Located in the historic Bhabra Bazaar, Abbasi’s shop, lit up by a few naked light bulbs, is among a dwindling number of antique restoration workshops in the garrison city. The 71-year-old inherited the craft from his forefathers and set up the shop nearly 40 years ago in 1985, now employing three workers who help him repair, polish and electroplate copper and brass relics to be sold to customers in Pakistan and abroad.
“Since then [1985] I’ve been in this business,” Abbasi told Arab News at his shop earlier this month as he dusted an antique bugle. “We purchase antique items and repair them and polish them and then sell them to our dedicated customers.” 
Buyers reach out to him from as far as the UK and US, he added. 
Abbasi mainly sources copper and brass items from households and scrap dealers, who scour heaps of imported items that first land at the port in Pakistan’s commercial hub of Karachi. 
“The traders who buy them, they contact us,” the craftsman said. “They are broken items, and we have to repair them and polish and recondition them to the extent that you cannot even tell that this was an old item.”
Antiques at Abbasi’s shop can sell for anywhere between $40 to $1,000, but the art of antique preservation and restoration is now at risk of being lost as the new generation is opting out of the profession. 
“The problem is that the craftsmen who used to work [on antiques] are no longer available. Not a lot of attention is given to this craft, The government has also not prioritized training craftsmen,” Abbasi lamented. 
“Antiquarians quit the business due to lack of business, and some passed away and the new generation isn’t interested in this line of work.”
Customers and collectors who frequent Abbasi’s shop often place orders after coming across antique items on the Internet.
“I have liked an antiques page [on social media]. I searched for an item on the Internet and told him [Abbasi] about it and he arranged it for me,” Dr. Ahmad Ali, an antique collector, told Arab News. “It was the same thing that I had ordered.”
Shamas Rehman, who has been a collector for over two decades, praised Abbasi’s fine craftsmanship. 
“My forefathers were collecting antiques, it was their hobby, and now I have been collecting them since 2003,” he said, “and from wherever we can get the antiques, we buy them, collect them and place them in our homes, and this goes on.”


Government orders police to ensure ceasefire after nine killed over property dispute in northwest Pakistan

Updated 26 July 2024
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Government orders police to ensure ceasefire after nine killed over property dispute in northwest Pakistan

  • The deadly and ongoing clashes over property dispute broke out on Wednesday 
  • Kurram has seen conflicts between tribes and religious groups in the past

PESHAWAR: The provincial administration of Pakistan's northwestern Khyber Pakhtunkhwa (KP) province on Friday instructed police to take necessary steps to end ongoing clashes in Kurram district over a property dispute, with nine people killed and dozens injured.

Located along Pakistan’s border with Afghanistan, the area has witnessed deadly conflicts among tribes and religious groups in the past as well as sectarian clashes and militant attacks. A major conflict that began in Kurram in 2007 continued for years before it was ended with the help of a jirga, a traditional assembly of tribal elders.

The current clash over a land dispute broke out on Wednesday and quickly spread to several villages and nearby settlements. 

According to an official statement circulated by the KP government, Chief Minister Ali Amin Gandapur directed the district administration and police to ensure a ceasefire.

“No one will be allowed to take the law into their own hands or disturb the peace of the area,” Gandapur was quoted as saying. “The administration and police must ensure the rule of government and law in the area. The parties to the dispute are also urged to resolve the property issue through a jirga according to tribal traditions.”

Syed Mir Hassan Jan, the Medical Superintendent at the District Headquarters Hospital in Kurram, said nine bodies and 58 injured people linked to the clashes had been brought to the hospital in the last three days.

The District Police Officer in Kurram, Nisar Ahmad Khan, said sporadic attacks were still ongoing.

“The conflict intensifies at night,” he said. “Sporadic exchange of fire has been going on between the tribes during the past two days.”

Khan said a large number of police and army personnel had been deployed at various locations to prevent clashes.

“The jirga, district administration, army and police have intervened to control the situation,” he added. 

The roads leading to Kurram have also been shut down since the clashes began.

“The entrances and exits were closed so that any third-party intervention could be avoided,” the DPO said.