Clinical trials begin for Egyptian COVID-19 vaccine

Egypt is to start clinical trials of its COVID-19 vaccine, EgyVax. (File/Shutterstock)
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Updated 02 March 2022
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Clinical trials begin for Egyptian COVID-19 vaccine

  • The announcement was made by Egyptian minister of higher education and scientific research, Khaled Abdel Ghaffar.

Egypt is to start clinical trials of its COVID-19 vaccine, EgyVax.

The announcement was made by Egyptian minister of higher education and scientific research, Khaled Abdel Ghaffar.

He said the trials represented “a very important development” and major success for Egypt in fighting the coronavirus pandemic, not only through its work with international organizations over the past two years but as a result of the efforts of a number of Egyptian scientists and researchers.

The minister added: “The new vaccine is the fruit of Egypt’s capabilities to produce and adopt vaccines globally, and it also reflects the amount of care given by the political leadership to this issue, by providing material and moral support to Egyptian scientists and researchers, believing in their distinguished scientific and research capabilities.

“Working on a 100 percent Egyptian vaccine is unprecedented, and we are cooperating with all national and international agencies to be assured that safety and effectiveness are at the highest level.”

Abdel Ghaffar pointed out that manufacturing the vaccine locally would provide a considerable amount of hard currency for the country.

“Transforming scientific research into a product is not an easy matter, but it is taking place according to in-depth studies and full cooperation between the various agencies representing the Egyptian state, and Eva Pharma (healthcare company), as it is one of the major manufacturing entities in the field of pharmaceutical industries in Egypt,” he said.

He noted that the Egyptian government was seeking to localize the vaccine industry via both the state-owned Vacsera holding company and the private sector.

Riad Armanious, chief executive officer of Eva Pharma, Egypt’s strategic partner in the manufacture of the vaccine, said work was underway to build vaccine manufacturing capabilities within Eva Pharma industrial complexes in 6th of October City, allowing the firm to make approximately 1.6 million doses per day.

He pointed out that the results of pre-clinical laboratory studies on animals showed an increase in antibodies in the blood against COVID-19 after two doses of EgyVax, adding that monitoring of side effects, blood analyzes, and chest X-rays gave promising indications about the safety and efficacy of the vaccine.

The Egyptian vaccine would be produced to meet the standards of the World Health Organization, and the US Food and Drug Administration, allowing it to be exported around the world, Armanious said, adding that production was expected to reach more than 500 million doses per year.


Iraq’s dreams of wheat independence dashed by water crisis 

Updated 11 min 8 sec ago
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Iraq’s dreams of wheat independence dashed by water crisis 

  • Iraq ranks fifth globally for climate risk
  • Average temperatures in Iraq have risen nearly half a degree Celsius per decade since 2000

NAJAF: Iraqi wheat farmer Ma’an Al-Fatlawi has long depended on the nearby Euphrates River to feed his fields near the city of Najaf. But this year, those waters, which made the Fertile Crescent a cradle of ancient civilization 10,000 years ago, are drying up, and he sees few options.
“Drilling wells is not successful in our land, because the water is saline,” Al-Fatlawi said, as he stood by an irrigation canal near his parched fields awaiting the release of his allotted water supply.
A push by Iraq — historically among the Middle East’s biggest wheat importers — to guarantee food security by ensuring wheat production covers the country’s needs has led to three successive annual surpluses of the staple grain.
But those hard-won advances are now under threat as the driest year in modern history and record-low water levels in the Tigris and Euphrates rivers have reduced planting and could slash the harvest by up to 50 percent this season.
“Iraq is facing one of the most severe droughts that has been observed in decades,” the UN Food and Agriculture Organization’s Iraq representative Salah El Hajj Hassan told Reuters.

VULNERABLE TO NATURE AND NEIGHBOURS
The crisis is laying bare Iraq’s vulnerability.
A largely desert nation, Iraq ranks fifth globally for climate risk, according to the UN’s Global Environment Outlook. Average temperatures in Iraq have risen nearly half a degree Celsius per decade since 2000 and could climb by up to 5.6 C by the end of the century compared to the period before industrialization, according to the International Energy Agency. Rainfall is projected to decline.
But Iraq is also at the mercy of its neighbors for 70 percent of its water supply. And Turkiye and Iran have been using upstream dams to take a greater share of the region’s shared resource.
The FAO says the diminishing amount of water that has trickled down to Iraq is the biggest factor behind the current crisis, which has forced Baghdad to introduce rationing.
Iraq’s water reserves have plunged from 60 billion cubic meters in 2020 to less than 4 billion today, said El Hajj Hassan, who expects wheat production this season to drop by 30 percent to 50 percent.
“Rain-fed and irrigated agriculture are directly affected nationwide,” he said.

EFFORTS TO END IMPORT DEPENDENCE UNDER THREAT
To wean the country off its dependence on imports, Iraq’s government has in recent years paid for high-yield seeds and inputs, promoted modern irrigation and desert farming to expand cultivation, and subsidised grain purchases to offer farmers more than double global wheat prices.
It is a plan that, though expensive, has boosted strategic wheat reserves to over 6 million metric tons in some seasons, overwhelming Iraq’s silo capacity. The government, which purchased around 5.1 million tons of the 2025 harvest, said in September that those reserves could meet up to a year of demand.
Others, however, including Harry Istepanian — a water expert and founder of Iraq Climate Change Center — now expect imports to rise again, putting the country at greater risk of higher food prices with knock-on effects for trade and government budgets.
“Iraq’s water and food security crisis is no longer just an environmental problem; it has immediate economic and security spillovers,” Istepanian told Reuters.
A preliminary FAO forecast anticipates wheat import needs for the 2025/26 marketing year to increase to about 2.4 million tons.
Global wheat markets are currently oversupplied, offering cheaper options, but Iraq could once again face price volatility.
Iraq’s trade ministry did not respond to a request for comment on the likelihood of increased imports.
In response to the crisis, the ministry of agriculture capped river-irrigated wheat at 1 million dunams in the 2025/26 season — half last season’s level — and mandated modern irrigation techniques including drip and sprinkler systems to replace flood irrigation through open canals, which loses water through evaporation and seepage.
A dunam is a measurement of area roughly equivalent to a quarter acre.
The ministry is allocating 3.5 million dunams in desert areas using groundwater. That too is contingent on the use of modern irrigation.
“The plan was implemented in two phases,” said Mahdi Dhamad Al-Qaisi, an adviser to the agriculture minister. “Both require modern irrigation.”
Rice cultivation, meanwhile, which is far more water-intensive than wheat, was banned nationwide.

RURAL LIVELIHOODS AT RISK
One ton of wheat production in Iraq requires about 1,100 cubic meters of water, said Ammar Abdul-Khaliq, head of the Wells and Groundwater Authority in southern Iraq. Pivoting to more dependence on wells to replace river water is risky.
“If water extraction continues without scientific study, groundwater reserves will decline,” he said.
Basra aquifers, he said, have already fallen by three to five meters.
Groundwater irrigation systems are also expensive due to the required infrastructure like sprinklers and concrete basins. That presents a further economic challenge to rural Iraqis, who make up around 30 percent of the population.
Some 170,000 people have already been displaced in rural areas due to water scarcity, the FAO’s El Hajj Hassan said.
“This is not a matter of only food security,” he said. “It’s worse when we look at it from the perspective of livelihoods.”
At his farm in Najaf, Al-Fatlawi is now experiencing that first-hand, having cut his wheat acreage to a fifth of its normal level this season and laid off all but two of his 10 workers.
“We rely on river water,” he said.