Pakistani friends, classmates proud of pig-to-human heart transplant pioneer

This handout photo released by the University of Maryland School of Medicine shows surgeons performing a transplant of a heart from a genetically modified pig to patient David Bennett, Sr., in Baltimore, Maryland, U.S., on January 7, 2022. (AFP)
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Updated 22 January 2022
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Pakistani friends, classmates proud of pig-to-human heart transplant pioneer

  • Pakistan-born doctor is co-founder of US program that successfully transplanted a pig heart into an American man
  • Muhammad Mansoor Mohiuddin attended Karachi’s Dow Medical College in the 1980s

KARACHI: Friends and former classmates of the Pakistan-born surgeon behind the world’s first pig-to-human heart transplant say they earmarked him for greatness from his medical school days.
Karachi-born Muhammad Mansoor Mohiuddin made headlines last week as the co-founder of the US university program that successfully transplanted the heart of a genetically modified pig into a gravely ill American man.
While hailed as a medical breakthrough, the procedure also raised ethical questions — particularly among some Jews and Muslims, who consider pigs to be unclean and avoid pork products.
None of that worried Mohiuddin’s friends and former colleagues in Pakistan, who remember him as an ace student with a passion for medicine.
“He would be so interested, always there, always available and always ready to get involved in surgery,” said Muneer Amanullah, a specialist who attended Karachi’s Dow Medical College with Mohiuddin in the 1980s.
College vice-chancellor Muhammad Saeed Qureshi said pride in Mohiuddin’s achievement had flooded the campus.
“There was exhilaration that this has been done by a graduate from this college,” he told AFP.




In this picture taken on January 13, 2022, Muhammad Saeed Qureshi, vice-chancellor of the Dow Medical College where Pakistan-born surgeon Muhammad Mansoor Mohiuddin studied in the 1980s, speaks during an interview with AFP in Karachi. (AFP)

Mohiuddin was quick to share the limelight with a team of 50 from the University of Maryland Medical School.
“They were all experts of their respective fields,” he told AFP by phone.
“They are the best surgeons, the best physicians, the best anaesthetists, and so on.”
While the prognosis for the recipient of the pig’s heart is far from certain, the surgery represents a major milestone for animal-to-human transplants.
About 110,000 Americans are currently waiting for an organ transplant, and more than 6,000 patients die each year before getting one, according to official figures.
To meet demand, doctors have long been interested in so-called xenotransplantation, or cross-species organ donation.
“We were working on this model for 18 years,” Mohiuddin said.
“Those 18 years were dotted with different phases of frustration — as well as breakthroughs — but finally we have done it.”




In this picture taken on January 13, 2022, students gather at a yard of the Dow University of Health Sciences, where Pakistan-born surgeon Muhammad Mansoor Mohiuddin studied in the 1980s, in Karachi, Pakistan. (AFP)

The surgery is not without controversy, however, especially given Mohiuddin’s Islamic faith.
Pigs are considered unclean by Muslims and Jews — and even some Christians who follow the Bible’s Old Testament literally.
“In my view, this is not permissible for a Muslim,” said Javed Ahmed Ghamdi, a prominent Islamic scholar, in a video blog where he discussed the procedure.
But another Islamic scholar in Pakistan gave the procedure a clean bill of health.
“There is no prohibition in sharia,” Allama Hasan Zafar Naqvi told AFP, calling it a “medical miracle.”
“In religion, no deed is as supreme as saving a human life,” added Mohiuddin.
In Karachi, the surgeon’s fellow alumni feel their former colleague may now be destined for even greater glory — medicine’s top prize.
“I think... the whole team is in for it, in for the Nobel Prize,” said vice-chancellor Qureshi.


Pakistan says responding to Afghan ‘offensive operations’ after border fire as tensions escalate

Updated 26 February 2026
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Pakistan says responding to Afghan ‘offensive operations’ after border fire as tensions escalate

  • Afghan Taliban spokesperson says “large-scale offensive operations” launched against Pakistani military bases
  • Pakistan says Afghan forces opened “unprovoked” fire across multiple sectors along shared border

ISLAMABAD: Afghanistan’s Taliban authorities said on Thursday they had launched “large-scale offensive operations” against Pakistani military bases and installations, prompting Pakistan to say its forces were responding to what it described as unprovoked fire along the shared border.

The escalation follows Islamabad’s weekend airstrikes targeting what it said were Tehreek-e-Taliban Pakistan (TTP) and Daesh militant camps inside Afghanistan in response to a wave of recent bombings and attacks in Pakistan. Islamabad said the strikes killed over 100 militants, while Kabul said dozens of civilians were killed and condemned the attacks as a violation of its sovereignty.

In a post on social media platform X, Afghan government spokesperson Zabihullah Mujahid said Afghanistan had launched “large-scale offensive operations” in response to repeated violations by the Pakistani military.

 

 

Pakistan’s Ministry of Information said Afghan forces had initiated hostilities along multiple points of the frontier.

“Afghan Taliban regime unprovoked action along the Pakistan–Afghanistan border given an immediate, and effective response,” the ministry said in a statement.

The statement said Pakistani forces were targeting Taliban positions in the Chitral, Khyber, Mohmand, Kurram and Bajaur sectors, claiming heavy Afghan casualties and the destruction of multiple posts and equipment. It added that Pakistan would take all necessary measures to safeguard its territorial integrity and the security of its citizens.

 

 

Separately, security officials said Pakistani forces had carried out counterattacks in several border sectors.

“Pakistan’s security forces are giving a befitting reply to the unprovoked Afghan aggression with full force,” a security official said, declining to be named. 

“The Pakistani security forces’ counter-attack destroyed Taliban’s hideouts and the Khawarij fled,” they added, referring to TTP militants. 

The claims from both sides could not be independently verified.

Cross-border violence has intensified in recent weeks, with Pakistan blaming a surge in suicide bombings and militant attacks on militants it says are based in Afghanistan. Kabul denies providing safe havens to anti-Pakistan militant groups.

The clashes mark the third major escalation between the neighbors in less than a year. Similar Pakistani strikes last year triggered weeklong clashes before Qatar, Türkiye and other regional actors mediated a ceasefire in October.

The 2,600-kilometer (1,600-mile) frontier, a key trade and transit corridor linking Pakistan to landlocked Afghanistan and onward to Central Asia, has faced repeated closures amid tensions, disrupting commerce and humanitarian movement. Trade between the two nations has remained closed since October 2025.