Pfizer set to oust AstraZeneca as top supplier of COVID-19 shots to poor nations

The expected change comes with headaches for receiving countries that lack sufficient cold storage capacity to handle the Pfizer vaccine. (File/AFP)
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Updated 15 December 2021
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Pfizer set to oust AstraZeneca as top supplier of COVID-19 shots to poor nations

  • The program has so far delivered more than 600 million shots to nearly 150 countries, of which more than 220 million are AstraZeneca’s and about 160 million Pfizer’s
  • By the end of March, another 150 million Pfizer doses are to be distributed by COVAX

BRUSSELS: Pfizer and BioNtech are set to displace AstraZeneca as the main suppliers of COVID-19 vaccines to the global COVAX program at the start of 2022, a shift that shows the increasing importance of their shot for poorer states.
The expected change comes with headaches for receiving countries that lack sufficient cold storage capacity to handle the Pfizer vaccine, and amid risks of a shortage of syringes needed to administer that shot.
AstraZeneca is currently the most distributed vaccine by COVAX, according to data from Gavi, the vaccine alliance that co-manages the program with the World Health Organization (WHO).
The program has so far delivered more than 600 million shots to nearly 150 countries, of which more than 220 million are AstraZeneca’s and about 160 million Pfizer’s.
But in the first quarter of next year Pfizer is set to take over, according to Gavi and WHO figures on doses assigned by the COVAX program for future supplies.
By the end of March, another 150 million Pfizer doses are to be distributed by COVAX, a WHO document shows.
A spokesperson for Gavi confirmed that Pfizer is far ahead in terms of “allocated” jabs, with about 470 million doses delivered or readied for delivery, against 350 million from AstraZeneca.
Pfizer is the first provider of COVID-19 vaccines to the European Union, the United States and Japan.
It has bilateral agreements for more than 6 billion doses, making it by far the largest supplier of COVID-19 vaccines, according to data from UNICEF, a UN agency.
But AstraZeneca has been seen as a crucial supplier to less developed countries, because its shot is cheaper and easier to deliver.
COVAX bet heavily on AstraZeneca at the beginning of the pandemic, but supply problems and export restrictions from top producer India gradually reduced its reliance on the Anglo-Swedish shot.
As the program faced problems in securing doses directly from vaccine makers amid a global scramble for shots, donations from rich nations became more important, turning Pfizer into the main supplier to COVAX. The United States is donating mostly Pfizer shots to the program.

COLD CHAIN AND SYRINGES
The change forced Gavi to rush to invest more in cold chain capacity in receiving countries that do not have enough refrigerators and cold transport equipment to handle the Pfizer shot, which requires lower storage temperatures than the AstraZeneca vaccine.
The organization warned about insufficient cold chain capacity in some countries, according to an internal report submitted to Gavi’s board at the beginning of December and seen by Reuters.
The problem is compounded by a risk of shortages of special syringes needed to administer the Pfizer vaccine, Gavi warned in the document.
The Pfizer jab is “the hardest to deliver given ultra-cold chain and special syringe requirements,” Gavi says in its internal document.
It is also “the hardest to plan for as these (donated vaccines) often come with earmarking and little notice or in a staggered manner and in small volumes and with short shelf lives,” the document says.
Wealthy countries donating COVID-19 vaccines with a relatively short shelf life has been a “major problem” for COVAX, a WHO official said last week, as many doses were wasted.
An EU official told a news briefing last week that EU donations of Pfizer vaccines to COVAX were slowed by a lack of syringes. A second official familiar with the issue told Reuters that Gavi had to postpone the delivery of some Pfizer doses from Europe because of the lack of syringes.
Pfizer declined to comment on syringes because it said it does not produce or buy them directly.
As more doses are made available to poorer nations, UNICEF and the WHO have long been warning of the insufficient supply of the auto-disable syringes, which are crucial for inoculations in poorer nations.
Auto-disable syringes lock automatically to prevent re-use, which is otherwise common in poorer nations and could spread of diseases. To make things more complicated, auto-disable syringes needed for the Pfizer vaccine are different from standard syringes, UNICEF said.


Shamima Begum’s case revived after top European court’s intervention

Shamima Begum left east London aged 15 and traveled to Daesh-held territory in Syria in 2015. (File/AFP)
Updated 11 sec ago
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Shamima Begum’s case revived after top European court’s intervention

  • European Court of Human Rights challenges British govt’s citizenship deprivation order
  • Begum, 26, left London as a teenager to marry a Daesh fighter, with concerns she was trafficked

LONDON: The longtime appeal by Shamima Begum to return to the UK has been revived after the European Court of Human Rights challenged the British government’s block on her return.

The 26-year-old, who left east London aged 15 and traveled to Daesh-held territory in Syria in 2015, had her British citizenship stripped by the then home secretary, Sajid Javid, The Times reported.

The Strasbourg court’s intervention means the UK must now consider if it acted unlawfully under the framework of the European Convention of Human Rights in stripping her citizenship in 2019.

Begum traveled with two friends to Syria. There, she became a child bride to Dutch national Yago Riedijk and had three children who all died as infants.

The court is examining whether the 2019 decision breached the ECHR’s Article Four, which prohibits slavery, servitude and forced labor.

As part of the examination, it could be found that the UK failed in its duty to identify Begum as a potential victim of trafficking and protect her from harm.

Begum’s journey to Syria made national headlines in the UK. The Times newspaper later discovered her whereabouts at a prison camp in Syria operated by Kurdish security forces, where she remains today.

In stripping her citizenship, Javid said the decision was “conducive to the public good.”

He also argued she was eligible for Bangladeshi nationality through her parents, to avoid rendering her stateless.

However, Bangladesh has said repeatedly that Begum is not a citizen of the country.

Begum’s lawyers, from the firm Birnberg Peirce, filed a submission to the Strasbourg court which argued that the UK failed to ask fundamental questions before stripping her citizenship, including concerns over child trafficking.

Gareth Peirce said the UK could now confront previously ignored questions as a result of the court’s intervention, providing “an unprecedented opportunity.”

She added: “It is impossible to dispute that a 15-year-old British child was lured and deceived for the purposes of sexual exploitation.

“It is equally impossible not to acknowledge the catalogue of failures to protect a child known to be at risk.”

The Strasbourg court’s move meant that it was “impossible now not to have real hope of a resolution,” she said, adding that the Begum case raised profound questions about the UK’s responsibility to victims of grooming and trafficking.

Despite years of litigation, Begum has failed to overturn the citizenship deprivation order. She has stated her desire to return to Britain.

In 2020, the Special Immigration Appeals Commission found that conditions in the camp where she is held, Al-Roj, were inhuman and degrading, but that national security considerations prevented any change to her case.

Later, the Supreme Court ruled that Begum was ineligible to return to Britain to take part in the appeal against her citizenship deprivation.

The Strasbourg court could reject appeals by Begum’s lawyers after considering the UK Home Office’s response to its questions.

If the latest appeal is upheld, however, ministers would have to “take account” of the court’s judgment. The court’s rulings are technically binding but lack an enforcement mechanism.

The Strasbourg court is now set to consider written submissions from both sides before deciding whether the case should proceed to a full hearing. A final judgment could take many months.

A Home Office spokesman said: “The government will always protect the UK and its citizens. That is why Shamima Begum — who posed a national security threat — had her British citizenship revoked and is unable to return to the UK.

“We will robustly defend any decision made to protect our national security.”

Maya Foa, CEO of Reprieve, a charity that has campaigned for the return of women and children from Syria, said: “This case only reached the European court because successive UK governments failed to take simple steps to resolve a common problem.

“While our security allies have all been bringing their people home, Britain has been burying its head in the sand. Casting British men, women and children into a legal black hole is a negligent policy that betrays a lack of faith in our justice system.”