DUBAI: Kid-size doses of Pfizer’s COVID-19 vaccine appear safe and nearly 91 percent effective at preventing symptomatic infections in 5- to 11-year-olds, according to study details released Friday as the US considers opening vaccinations to that age group.
The shots could begin in early November — with the first children in line fully protected by Christmas — if regulators give the go-ahead.
Details of Pfizer’s study were posted online. The Food and Drug Administration was expected to post its independent review of the company’s safety and effectiveness data later in the day.
Advisers to the FDA will publicly debate the evidence next week. If the agency ultimately authorizes the shots, the Centers for Disease Control and Prevention will make the final decision on who should receive them.
Full-strength Pfizer shots already are authorized for anyone 12 or older, but pediatricians and many parents are anxiously awaiting protection for younger children to stem rising infections from the extra-contagious delta variant and help keep kids in school.
More than 25,000 pediatricians and primary care providers already have signed up to get the shots into little arms.
The Biden administration has purchased enough kid-size doses — in special orange-capped vials to distinguish them from adult vaccine — for the nation’s roughly 28 million 5- to 11-year-olds. If the vaccine is cleared, millions of doses will be promptly shipped around the country, along with kid-size needles.
A Pfizer study tracked 2,268 kids in that age group who got two shots three weeks apart of either a placebo or the low-dose vaccine. Each dose was one-third the amount given to teens and adults.
Researchers calculated the low-dose vaccine was nearly 91 percent effective, based on 16 COVID-19 cases in youngsters given dummy shots versus three cases among vaccinated children. There were no severe illnesses reported among any of the youngsters, but the vaccinated ones had much milder symptoms than their unvaccinated counterparts.
In addition, young children given the low-dose shots developed coronavirus-fighting antibody levels just as strong as teens and young adults who got regular-strength vaccinations.
That’s important information considering that hospitalizations of mostly unvaccinated children reached record levels last month.
The CDC reported earlier this week that even as the delta mutant surged between June and September, Pfizer vaccinations were 93 percent effective at preventing hospitalizations among 12- to 18-year-olds.
Pfizer’s study of younger kids found the low-dose shots proved safe, with similar or fewer temporary side effects such as sore arms, fever or achiness that teens experience.
The study isn’t large enough to detect any extremely rare side effects, such as the heart inflammation that occasionally occurs after the second dose, mostly in young men.
While children run a lower risk of severe illness or death than older people, COVID-19 has killed more than 630 Americans 18 and under, according to the CDC. Nearly 6.2 million children have been infected with the coronavirus, more than 1.1 million in the last six weeks as the delta mutant surged, the American Academy of Pediatrics says.
Moderna also is studying its COVID-19 shots in elementary school-age youngsters. Pfizer and Moderna are studying even younger children as well, down to 6-month-olds. Results are expected later in the year.
Pfizer says COVID-19 vaccine more than 90 percent effective in kids
https://arab.news/bbkxq
Pfizer says COVID-19 vaccine more than 90 percent effective in kids
- Shots could begin in early November with the first children in line fully protected by Christmas if regulators give the go-ahead
- FDA was expected to post its independent review of the company's safety and effectiveness data later in the day
Pakistanis fleeing Iran describe strikes shaking ground under their feet
- Nearly 1,000 students, businessmen and pilgrims have fled Iran since the war started out of a total 35,000 Pakistanis in the country
QUETTA: Pakistanis fleeing Iran described explosions and missile strikes across Tehran shaking the ground under their feet and engulfing buildings in fire and smoke in a city emptied of many of its residents. The conflict has widened sharply, with a US submarine sinking an Iranian warship off Sri Lanka on Wednesday and NATO air defenses destroying an Iranian missile fired toward Turkiye.
Governments have been scrambling to evacuate stranded citizens, with most of the region’s airspace closed due to the risk of missiles hitting passenger planes.
“I was in the classroom when a powerful explosion rocked our university building,” Hareem Zahra, 23, a student at the Tehran University of Engineering, told Reuters after crossing Pakistan’s land border with Iran.
“We saw thick smoke coming from many buildings on fire,” she said, adding Tehran was under attack until the moment she left.
TEHRAN LOOKED DESERTED
Nearly 1,000 students, businessmen and pilgrims have fled Iran since the war started out of a total 35,000 Pakistanis in the country, Mudassir Tipu, Pakistan’s ambassador to Tehran, said.
“There are now serious challenges. As you know there is no Internet in most parts of Iran,” he said. Iran has retaliated with a barrage of ballistic missiles targeting Israel and Washington’s allies in the Gulf, including Qatar, Kuwait, the UAE, and Saudi Arabia, following US and Israeli air strikes that killed Supreme Leader Ayatollah Ali Khamenei on Saturday.
Tehran has looked deserted since the conflict began, said Nadir Abbas, 25, a student of Persian literature at a university in the Iranian capital.
“I saw a drone hit a basketball court where six girl players lost their lives.”
Reuters could not verify his account.
DESTRUCTION EVERYWHERE
Islamabad is walking a diplomatic tightrope as it attempts to maintain warming ties with Washington while expressing solidarity with Iran.
Pakistan is home to the second-largest Shiite population in the world after Iran and being drawn into the conflict could lead to instability at home as well as complications evacuating its citizens.
“The first attack happened right next to my hospital,” said Sakhi Aun Mohammad, a student at Tehran University of Medical Sciences. After he reached the border, an Iranian friend called to check if he was safe, saying: “’Thank God, you have gone to Pakistan, all of you are safe, but your hostel has been attacked’.” A Pakistani diplomat who is still in Tehran said attacks took place every four or five hours, adding one missile struck a building next to his office. “At times you will feel as if something exploded right at your feet,” he said. “The last time I got out was at night. Buildings had collapsed, some others were on fire. There is destruction everywhere.”
He added: “It is almost like a ghost town.”
