AstraZeneca COVID-19 vaccine trial volunteer has died, Brazil health authority says

The regulator said testing of the vaccine would continue after the volunteer’s death. It provided no further details, citing medical confidentiality of those involved in trials. (AP/File Photo)
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Updated 21 October 2020
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AstraZeneca COVID-19 vaccine trial volunteer has died, Brazil health authority says

  • Regulator said testing of the vaccine would continue after the volunteer’s death

SAO PAULO: Brazilian health authority Anvisa said on Wednesday that a volunteer in a clinical trial of the COVID-19 vaccine developed by AstraZeneca and Oxford University has died, stating it had received data from an investigation into the matter.
The regulator said testing of the vaccine would continue after the volunteer’s death. It provided no further details, citing medical confidentiality of those involved in trials.
The Federal University of Sao Paulo, which is helping coordinate phase 3 clinical trials in Brazil, separately said that the volunteer was Brazilian but did not say where the person lived.
AstraZeneca shares turned negative and were down 1.7%.
The federal government already has plans to purchase the UK vaccine and produce it at its biomedical research center FioCruz in Rio de Janeiro, while a competing vaccine from China’s Sinovac is being tested by Sao Paulo state’s research center Butantan Institute.
Brazil has the second deadliest outbreak of coronavirus, with more than 154,000 killed by COVID-19, following only the United States. It is the third worst outbreak in terms of cases, with more than 5.2 million infected, after the United States and India.


Trump’s Iran war violates international law, experts say

Updated 06 March 2026
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Trump’s Iran war violates international law, experts say

  • Mary Ellen O’Connell, a professor at the University of Notre Dame, said the attack on Iran “had no justification under international law“
  • “The US probably could have prevented any Israeli attack on Iran by virtue of the leverage afforded by critical US military support,” said Finucane

WASHINGTON: The United States insists it attacked Iran to curb “direct threats” from the Islamic republic, but legal experts say the dangers cited by Washington do not justify war under international law.
US and Israeli forces launched a massive air campaign against Iran on February 28, with Washington saying it aimed to curb nuclear and missile threats from Tehran. Yet the war has also decapitated the country’s government, and President Donald Trump is now demanding “unconditional surrender.”
The White House laid out Washington’s justification for the war during a news conference this week.
“This decision to launch this operation was based on a cumulative effect of various direct threats that Iran posed to the United States of America, and the president’s feeling, based on fact, that Iran does pose (an) imminent and direct threat,” Press Secretary Karoline Leavitt said Wednesday.
She went on to cite Iranian sponsorship of “terrorism,” its ballistic missile program and its alleged efforts to “create nuclear weapons and nuclear bombs.”
But Mary Ellen O’Connell, a professor at the University of Notre Dame, said the attack on Iran “had no justification under international law.”
“The law is clear that international disputes are to be resolved using peaceful means — negotiation, mediation, the intervention of international organizations,” said O’Connell, an expert in international law on the use of force and international legal theory.
The Trump administration has offered “vague mentions of imminent attacks by Iran and to prevent Iran from acquiring a nuclear weapon,” while the UN Charter “requires, at the least, that evidence of a significant attack by Iran be underway,” she said.

- ‘Even less plausible’ -

“No shred of such evidence has been provided. Nor is there any right whatsoever to start a war over a weapons program.”
While Leavitt cited threats from missiles and militants, US Secretary of State Marco Rubio offered a different justification for the war earlier in the week: fears that an Israeli attack would trigger reprisals against US forces.
Brian Finucane, senior adviser for the International Crisis Group’s US Program, said there were several issues with Rubio’s explanation, including that the Trump administration has since offered other rationales for the war.
“The US probably could have prevented any Israeli attack on Iran by virtue of the leverage afforded by critical US military support,” said Finucane, who previously worked in the Office of the Legal Adviser at the US Department of State.
The Iran war is not the only legally dubious military intervention by the Trump administration.
In early September, the United States began carrying out strikes on alleged drug-smuggling boats in the Caribbean and later the eastern Pacific — a campaign that has killed more than 150 people.
The US government has yet to provide definitive evidence that the vessels it targets are involved in drug trafficking, and legal experts and rights groups say the strikes likely amount to extrajudicial killings.
Trump also ordered strikes on Iranian nuclear sites last year, and sent US forces into Caracas in early January to seize leftist Venezuelan leader Nicolas Maduro, who is now on trial in the United States.
Finucane said Trump’s Friday demand for “unconditional surrender” by Iran “further undercuts prior justifications for US military action.”
“The administration has not even bothered to argue that Operation Epic Fury complies with international law, but certainly statements like this make any such argument even less plausible,” he said, referring to the Iran operation.