SAO PAULO: Brazilian health authority Anvisa said on Wednesday that a volunteer in a clinical trial of the COVID-19 vaccine developed by AstraZeneca and Oxford University has died, stating it had received data from an investigation into the matter.
The regulator said testing of the vaccine would continue after the volunteer’s death. It provided no further details, citing medical confidentiality of those involved in trials.
The Federal University of Sao Paulo, which is helping coordinate phase 3 clinical trials in Brazil, separately said that the volunteer was Brazilian but did not say where the person lived.
AstraZeneca shares turned negative and were down 1.7%.
The federal government already has plans to purchase the UK vaccine and produce it at its biomedical research center FioCruz in Rio de Janeiro, while a competing vaccine from China’s Sinovac is being tested by Sao Paulo state’s research center Butantan Institute.
Brazil has the second deadliest outbreak of coronavirus, with more than 154,000 killed by COVID-19, following only the United States. It is the third worst outbreak in terms of cases, with more than 5.2 million infected, after the United States and India.
AstraZeneca COVID-19 vaccine trial volunteer has died, Brazil health authority says
https://arab.news/cgmzx
AstraZeneca COVID-19 vaccine trial volunteer has died, Brazil health authority says
- Regulator said testing of the vaccine would continue after the volunteer’s death
India rolls out strictest anti-pollution curbs as toxic smog engulfs Delhi
- Private monitors in several parts of northern Delhi recorded AQI spikes between 550 and 700s
- Authorities invoked stage four of the capital region’s emergency pollution-control framework
NEW DELHI: India’s capital choked under a thick blanket of smog on Sunday, with the government imposing anti-pollution curbs after monitoring stations in some areas recorded extremely hazardous air quality.
Home to 30 million people, Delhi has not recorded a single “clean air” day in 2025, with Air Quality Index readings hitting high above the 50 score throughout the year.
On the AQI scale from 0 to 500, good air quality is represented by levels below 50, while levels above 300 are dangerous.
Worsening since late October, official records over the weekend were in the severe to severe-plus range of 400–500, but as 24-hour averages, they did not capture the peaks. Private monitors in several parts of North and North West Delhi recorded AQI spikes above 550 and even into the 700s in real-time.
On Saturday evening, the Ministry of Environment’s Commission for Air Quality Management invoked stage four — the highest level — of the Graded Response Action Plan for Delhi and surrounding areas.
To “prevent further deterioration of air quality in the region,” the commission suspended all non-essential construction, shut stone crushers and mining operations, stopped entry of trucks into the capital region, and ordered schools to shift to hybrid classes or online, where possible.
While authorities blamed the pollution on “adverse meteorological conditions,” residents have been demanding more government action.
“The situation is so bad in Delhi that we don’t have any option but to force kids to do online classes. The government has failed us; it has not done anything to address the issue,” said Nabanita Nayak, who decided for her teenage children to attend school online only, despite concerns over their screen addiction.
“If the kids are too much in front of laptops, that’s also an issue. As a mother, I am worried.”
Delhi’s pollution has been worsening since Diwali in late October, when the average AQI has been above 370, or “very poor.” Since mid-November, it has been over 400, which means “severe” air quality, with certain areas recording 500 and above, which is classified as a “hazardous” level.
“I don’t feel proud living in Delhi. It’s the capital city of the country … We talk about being a developed nation by 2047 — we have deadlines,” said Jagriti Arora, who is keeping her 7-year-old daughter at home to prevent allergy flare-ups caused by air pollution.
“The government has to do something … China had a big problem with pollution, but now they’ve managed to bring it down.”
Delhi’s air quality deteriorates in winter due to local emissions and seasonal weather conditions. Cold temperatures and low wind speeds result in a temperature inversion, which traps pollutants close to the ground instead of letting them disperse. This allows emissions from millions of vehicles, ongoing construction, and nearby industrial activity to accumulate in the air. Urban waste burning and dust from construction sites further add to it.
“This is not a new thing. This has been happening now for over 10 years,” Arora said. “You can see it. You don’t need to actually look at an AQI meter to see how bad the pollution is these days.”
