KARACHI: Pakistani researchers working under government-approved projects have expressed confidence that they can develop a vaccine for coronavirus, but added that the process could take nine months or more.
As of Sunday, authorities said 50 people had died while 3,200 had tested positive for the virus in the country.
“We are actively engaged in vaccination development. It will be clinical trials on animals first and then humans... the process will not take less than nine months, could even take more than that.”
Dr. Javed Akram, who is leading a government-sanctioned series of clinical trials for the vaccine, told Arab News on Saturday.
Dr. Akram, who is also a Vice-Chancellor of the University of Health Sciences (UHS) in Lahore, said that the process began on Friday after Professor Dr. Atta-ur-Rahman, Chairman of Prime Minister’s National Task Force on Science and Technology authorized him to lead the clinical trials for the vaccine, last week.
It follows a breakthrough by Pakistani scientists and researchers who detected a genetic mutation of the coronavirus through genome sequencing – a process which reveals the order of bases present in the entire genome of an organism and is an essential step in the necessary research for clinical diagnosis and the development of vaccines and drugs.
Since the breakthrough, Dr. Akram said they had conducted genome sequencing for the coronavirus in two separate trials, in Karachi and Lahore.
Experts say the studies reveal that the virus is mutative, which means that “it can adjust to local conditions” which are slightly different from Wuhan – the epicenter of the epidemic in China which led to the coronavirus outbreak, killing more than 65,000 and impacting more than a million people across the world.
“The process revealed that the sequence of this virus is slightly different from the Wuhan virus with few mutations,” Professor Dr. Saeed Khan, a virologist at Dow University of Health Sciences (DUHS) in Karachi, and a member of the team that conducted the trials told Arab News.
On Wednesday, DUHS said it had conducted the genetic sequencing of the virus – obtained from a locally-infected 15-year-old boy – by collaborating with the International Center for Chemical and Biological Sciences (ICCBS) in Karachi.
Dr. Akram confirmed that the tests showed that the coronavirus’ strain in Pakistan was mutative but said that it was not “clinically significant.”
“We have also done (genetic sequencing) and (it was detected) that mutations of the virus are taking place, but they are not very significant because these changes are not major – only 3-5 percent mutations are detected,” he said.
The research further revealed that two types of coronavirus strains, S-Strain and L-Strain, are spreading around the world.
“The study shows that the L-strain was derived from the older S-strain. The genetic sequencing shows that the virus was L-strain that is more aggressive and spreads rapidly,” Professor Khan said.
DUHS now plans to develop the vaccines, which researchers say requires funding – a request for which has been sent to the relevant authorities.
“We want to develop a vaccine that would be effective for all strains of the virus,” Professor Khan said.
Pakistani scientists get government nod to develop coronavirus vaccine
https://arab.news/p8yxp
Pakistani scientists get government nod to develop coronavirus vaccine
- Researchers say process awaits funding, could take nine months or more
- Clinical trials conducted after experts detected a genetic mutation of the virus through genome sequencing
Imran Khan not a ‘national security threat,’ ex-PM’s party responds to Pakistan military
- Pakistan’s military spokesperson on Friday described Khan’s anti-army narrative as a “national security threat”
- PTI Chairman Gohar Ali Khan says words used by military spokesperson for Khan were “not appropriate”
ISLAMABAD: Former prime minister Imran Khan’s Pakistan Tehreek-e-Insaf (PTI) party on Saturday responded to allegations by Pakistan military spokesperson Lt. Gen. Ahmed Sharif Chaudhry from a day earlier, saying that he was not a “national security threat.”
Chaudhry, who heads the military’s media wing as director general of the Inter-Services Public Relations (ISPR), spoke to journalists on Friday, in which he referred to Khan as a “mentally ill” person several times during the press interaction. Chaudhry described Khan’s anti-army narrative as a “national security threat.”
The military spokesperson was responding to Khan’s social media post this week in which he accused Chief of Defense Forces Field Marshal Asim Munir of being responsible for “the complete collapse of the constitution and rule of law in Pakistan.”
“The people of Pakistan stand with Imran Khan, they stand with PTI,” the party’s secretary-general, Salman Akram Raja, told reporters during a news conference.
“Imran Khan is not a national security threat. Imran Khan has kept the people of this country united.”
Raja said there were several narratives in the country, including those that created tensions along ethnic and sectarian lines, but Khan had rejected all of them and stood with one that the people of Pakistan supported.
PTI Chairman Gohar Ali Khan, flanked by Raja, criticized the military spokesperson as well, saying his press talk on Thursday had “severely disappointed” him.
“The words that were used [by the military spokesperson] were not appropriate,” Gohar said. “Those words were wrong.”
‘NATURAL OUTCOME’
Speaking to reporters earlier on Saturday, Pakistan’s Defense Minister Khawaja Asif defended the military spokesperson’s remarks against Khan.
“When this kind of language is used for individuals as well as for institutions, then a reaction is a natural outcome,” he said.
“The same thing is happening on the Twitter accounts being run in his [Khan’s] name. If the DG ISPR has given any reaction to it, then I believe it was a very measured reaction.”
Khan, who was ousted after a parliamentary vote of confidence in April 2022, blames the country’s powerful military for removing him from power by colluding with his political opponents. Both deny the allegations.
The former prime minister, who has been in prison since August 2023 on a slew of charges he says are politically motivated, also alleges his party was denied victory by the army and his political rivals in the 2024 general election through rigging.
The army and the government both deny his allegations.
