WASHINGTON: The first human trial to evaluate a candidate vaccine against coronavirus disease 2019 has begun in Seattle, US health officials said Monday.
"The open-label trial will enroll 45 healthy adult volunteers ages 18 to 55 years over approximately 6 weeks," the US National Institutes of Health (NIH) said in a statement.
"The first participant received the investigational vaccine today."
But the candidate would still need to progress through various more stages, known as phases, to prove it works and is safe.
US officials have estimated it may take another year to 18 months before it becomes available -- if everything goes to plan.
The vaccine is called mRNA-1273 and was developed by NIH scientists and collaborators at biotechnology company Moderna, which is based in Cambridge, Massachusetts.
Funding was also provided by the Oslo-based Coalition for Epidemic Preparedness Innovations (CEPI).
"Finding a safe and effective vaccine to prevent infection with SARS-CoV-2 is an urgent public health priority," said Anthony Fauci, head of infectious diseases at the NIH.
"This Phase 1 study, launched in record speed, is an important first step toward achieving that goal."
Coronaviruses are spherical and have spikes protruding from their surface, giving them a crown-like appearance. The spike binds to human cells, allowing the virus to gain entry.
The Moderna candidate vaccine carries the genetic information of this spike in a substance called "messenger RNA."
Injecting human tissue with the spike's messenger RNA makes it grow inside the body, thereby eliciting an immune response without having actually infected a person with the full-blown virus.
US begins first human trial of coronavirus vaccine
https://arab.news/cmpub
US begins first human trial of coronavirus vaccine
- Dozens of research groups around the world are racing to create a vaccine as COVID-19 cases continue to grow
Brazil’s Lula urges Trump to treat all countries equally
NEW DELHI: Brazil’s President Luiz Inacio Lula da Silva urged Donald Trump on Sunday to treat all countries equally after the US leader imposed a 15 percent tariff on imports following an adverse Supreme Court ruling.
“I want to tell the US President Donald Trump that we don’t want a new Cold War. We don’t want interference in any other country, we want all countries to be treated equally,” Lula told reporters in New Delhi.
The conservative-majority Supreme Court ruled six to three on Friday that a 1977 law Trump has relied on to slap sudden levies on individual countries, upending global trade, “does not authorize the President to impose tariffs.”
Lula said he would not like to react to the Supreme Court decisions of another country, but hoped that Brazil’s relations with the United States “will go back to normalcy” soon.
The veteran leftist leader is expected to travel to Washington next month for a meeting with Trump.
“I am convinced that Brazil-US relation will go back to normalcy after our conversation,” Lula, 80, said, adding that Brazil only wanted to “live in peace, generate jobs, and improve the lives of our people.”
Lula and Trump, 79, stand on polar opposite sides when it comes to issues such as multilateralism, international trade and the fight against climate change.
However, ties between Brazil and the United States appear to be on the mend after months of animosity between Washington and Brasilia.
As a result, Trump’s administration has exempted key Brazilian exports from 40 percent tariffs that had been imposed on the South American country last year.
‘Affinity’
“The world doesn’t need more turbulence, it needs peace,” said Lula, who arrived in India on Wednesday for a summit on artificial intelligence and a bilateral meeting with Prime Minister Narendra Modi.
Ties between Washington and Brasilia soured in recent months, with Trump angered over the trial and conviction of his ally, the far-right former Brazil president Jair Bolsonaro.
Trump imposed sanctions against several top officials, including a Supreme Court judge, to punish Brazil for what he termed a “witch hunt” against Bolsonaro.
Bolsonaro was sentenced to 27 years in prison for his role in a botched coup bid after his 2022 election loss to Lula.
Lula said that, as the two largest democracies in the Americas, he looked forward to a positive relationship with the United States.
“We are two men of 80 years of age, so we cannot play around with democracy,” he said.
“We have to take this very seriously. We have to shake hands eye-to-eye, person-to-person, and to discuss what is best for the US and Brazil.”
Lula also praised Modi after India and Brazil agreed to boost cooperation on critical minerals and rare earths and signed a raft of other deals on Saturday.
“I have a lot of affinity with Prime Minister Modi,” he said.
Lula will travel to South Korea later on Sunday for meetings with President Lee Jae Myung and to attend a business forum.
