Getting measles ‘resets’ the body’s immune system

In this April 2019 photo, New York City Mayor Bill de Blasio speaks during a news conference declaring a public health emergency in parts of Brooklyn in response to a measles outbreak. Health experts are saying measles, which is once more on the rise globally, is more harmful than previously thought. (REUTERS/Shannon Stapleton/File Photo)
Updated 01 November 2019
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Getting measles ‘resets’ the body’s immune system

  • Netherlands study shows the virus erases the body’s memory of previous pathogens, effectively wiping its immunity memory

WASHINGTON: Measles, the contagious childhood disease that is once more on the rise globally, is more harmful than previously thought.
A new analysis of 77 unvaccinated children from the Netherlands carried out by an international team of researchers led by scientists at Harvard has found that the virus erases the body’s memory of previous pathogens — effectively wiping its immunity memory.
The virus eliminated between 11 and 73 percent of the children’s protective antibodies, blood proteins responsible for “remembering” previous encounters with disease, the team wrote in the journal Science on Thursday.
This left some of the children with immunity close to that of a newborn baby.


“It sort of resets your immune system back to sort of a more naive state,” Harvard epidemiologist and coauthor Michael Mena told AFP.
In order to rebuild their defenses, they will need to be exposed to numerous pathogens as they were in their infancy, he added.
To validate their result, the team then carried out experiments on macaque monkeys, with the animals losing 40-60 percent of their protective antibodies.
“The virus is much more deleterious than we realized, which means the vaccine is that much more valuable,” said study coauthor and Howard Hughes Medical Institute Investigator Stephen Elledge.

 


Apple to update EU browser options, make more apps deletable

Updated 22 August 2024
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Apple to update EU browser options, make more apps deletable

  • iPhone maker came under pressure from regulators to make changes after the EU’s sweeping Digital Markets Act took effect on March 7
  • Apple users will be able to select a default browser directly from the choice screen after going through a mandatory list of options

STOCKHOLM: Apple will change how users choose browser options in the European Union, add a dedicated section for changing default apps, and make more apps deletable, the company said on Thursday.
The iPhone maker came under pressure from regulators to make changes after the EU’s sweeping Digital Markets Act took effect on March 7, forcing big tech companies to offer mobile users the ability to select from a list of available web browsers on a “choice screen.”
The new rules require mobile software makers to show the choice screen where users can select a browser, search engine and virtual assistant as they set up their phones, which earlier came with preferred options from Apple and Google.
In an update later this year, Apple users will be able to select a default browser directly from the choice screen after going through a mandatory list of options.
A randomly ordered list of 12 browsers per EU country will be shown to the user with short descriptions, and the chosen one will be automatically downloaded, Apple said. The choice screen will also be available on iPads through an update later this year.
Apple released a previous update in response to the new rules in March, but browser companies criticized the design of its choice screen, and the Commission opened an investigation on March 25 saying it suspected that the measures fell short of effective compliance.
The company said it has been in dialogue with the European Commission and believes the new changes will address regulators’ concerns.
It also plans to introduce a dedicated area for default apps where a user will be able to set defaults for messaging, phone calls, spam filters, password managers and keyboards.
Users will also be able to delete certain Apple-made apps such as App Store, Messages, Camera, Photos and Safari. Only Settings and Phone apps would not be deletable.