What are the main talking points at US-Iran negotiations in Pakistan?

A man sits next to televisions at a shop showing news regarding the peace talks expected to be held in Islamabad by delegations from the United States and Iran, in Karachi, Pakistan, April 11, 2026. (Reuters)
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Updated 11 April 2026
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What are the main talking points at US-Iran negotiations in Pakistan?

  • Iran wants a ceasefire in Lebanon, Israel and the US have said Lebanon campaign not part of Iran-US ceasefire
  • Iran wants to be allowed to enrich uranium, which Washington has ruled out and Trump has insisted is non-negotiable

ISLAMABAD: Top US and Iranian officials gathered ‌in the Pakistani capital Islamabad on Saturday to hold talks that seek to end their war in the Middle East that ​has killed thousands, roiled energy supplies and hurt the global economy.

Here are the key issues the two sides are expected to discuss, with Tehran insisting that formal talks can begin only after Washington gives commitments on a ceasefire in Lebanon and lifting sanctions on Iran.

  • Iran wants a ceasefire in Lebanon, where Israeli attacks on Iran-backed Hezbollah ‌militants have killed ‌nearly 2,000 people since the start ​of ‌the ⁠fighting ​in March. ⁠Israel and the US have said the Lebanon campaign is not part of the Iran-US ceasefire while Tehran insists it is.
  •  Iran wants the US to unblock Iranian assets and end sanctions that have crippled its economy for years. Washington has indicated that it is open to significant sanctions ⁠relief but only in exchange for concessions ‌from Iran on its nuclear and ‌missile programs.
  •  Iran wants acknowledgment of ​its authority over the ‌Strait of Hormuz, where it aims to collect transit ‌fees and control access in what would amount to a huge shift in regional power. The US wants it opened for oil tankers and other traffic without any limitations, including tolls.
  • Iran is ‌expected to demand compensation for all damage during the six-week war. The US has not ⁠commented ⁠on this.
  • Iran wants to be allowed to enrich uranium, which Washington has ruled out and President Donald Trump has insisted is non-negotiable.
  • Israel and the US both want Iran’s missile capabilities to be dramatically curtailed. Tehran has said its formidable missile arsenal is non-negotiable.
  • Iran wants withdrawal of US combat forces from the region, cessation of war on all fronts and a commitment to non-aggression.

Trump has vowed to retain military assets in the Middle ​East until a peace ​deal is reached and warned of a major escalation in fighting if it failed to comply.