‘Nightmare bacteria’ cases are increasing in the US

A sign marks the entrance to the US Centers for Disease Control and Prevention headquarters in Atlanta. (AP Photo/File)
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Updated 26 September 2025
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‘Nightmare bacteria’ cases are increasing in the US

  • Bacteria that are difficult to treat due to the so-called NDM gene primarily drove the increase, CDC researchers say
  • 4,341 cases of carbapenem-resistant bacterial infections counted from 29 states in 2023, and that is just a partial count

NEW YORK: Infection rates from drug-resistant “nightmare bacteria” rose almost 70 percent between 2019 and 2023, according to a new report from Centers for Disease Control and Prevention scientists.
Bacteria that are difficult to treat due to the so-called NDM gene primarily drove the increase, CDC researchers wrote in an article published Monday in the Annals of Internal Medicine. Only two antibiotics work against those infections, and the drugs are expensive and must be administered through an IV, researchers said.
Bacteria with the gene were once considered exotic, linked to a small number of patients who received medical care overseas. Though the numbers are still small, the rate of US cases jumped more than fivefold in recent years, the researchers reported.
“The rise of NDMs in the US is a grave danger and very worrisome,” said David Weiss, an Emory University infectious diseases researcher, in an email.
It’s likely many people are unrecognized carriers of the drug-resistant bacteria, which could lead to community spread, the CDC scientists said.




This 2019 illustration provided by the Centers for Disease Control and Prevention depicts carbapenem-resistant Enterobacteriaceae bacteria. (CDC via AP)

That may play out in doctors’ offices across the country, as infections long considered routine — like urinary tract infections — could become harder to treat, said Dr. Maroya Walters, one of the report’s authors.
Antimicrobial resistance occurs when germs such as bacteria and fungi gain the power to fight off the drugs designed to kill them. The misuse of antibiotics was a big reason for the rise — unfinished or unnecessary prescriptions that didn’t kill the germs made them stronger.
In recent years, the CDC has drawn attention to ” nightmare bacteria ” resistant to a wide range of antibiotics. That includes carbapenems, a class of antibiotics considered a last resort for treatment of serious infections.
Researchers drew data from 29 states that do the necessary testing and reporting of carbapenem-resistant bacteria.
They counted 4,341 cases of carbapenem-resistant bacterial infections from those states in 2023, with 1,831 of them the NDM variety. The researchers did not say how many of the infected people died.
The rate of carbapenem-resistant infections rose from just under 2 per 100,000 people in 2019 to more than 3 per 100,000 in 2023 — an increase of 69 percent. But the rate of NDM cases rose from around 0.25 to about 1.35 — an increase of 460 percent, the authors said.
A researcher not involved in the study said the increase is probably related to the COVID-19 pandemic.
“We know that there was a huge surge in antibiotic use during the pandemic, so this likely is reflected in increasing drug resistance,” said Dr. Jason Burnham, a Washington University researcher, in an email.
The CDC’s count is only a partial picture.
Many states are not fully testing and reporting cases. Even in states that do, cases tend to be among hospital patients sick enough to warrant special testing. Many hospitals also aren’t able to do the testing needed to detect certain forms of genetic resistance.
The CDC researchers did not have data from some of the most populous states, including California, Florida, New York and Texas, which means the absolute number of US infections “is definitely underestimated,” Burnham said.
This is not the first study to report a rise. A CDC report published in June noted an increase in NDM cases in New York City between 2019 and 2024.

 


India’s Parliament approves bill to open civil nuclear power sector to private firms

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India’s Parliament approves bill to open civil nuclear power sector to private firms

  • The government termed it a major policy shift to speed up clean energy expansion
  • The move carries global significance as India seeks to position itself as a major player in the next wave of nuclear energy

NEW DELHI: India’s Parliament approved new legislation Thursday that enables opening the tightly controlled civil nuclear power sector to private companies.
The government termed it a major policy shift to speed up clean energy expansion while the opposition political parties argued that it dilutes safety and liability safeguards.
The lower house of parliament passed the legislation Wednesday and the upper house on Thursday. It now needs the assent from the Indian president, which is a formality, to come into force.
The move carries global significance as India seeks to position itself as a major player in the next wave of nuclear energy, including with small modular reactors at a time many nations are reassessing nuclear power to meet climate targets and reduce dependence on fossil fuels.
Supporters argue the legislation marks a decisive break from decades of state dominance in nuclear energy while critics say it opens the door to risks, mainly health hazards, that could have long term consequences.
“It marks a momentous milestone for India and signals capable private sector players that the country is open for business in the nuclear energy space,” said Karthik Ganesan, director of strategic partnerships at the Council on Energy, Environment and Water, a think tank.
Junior Minister Jitendra Singh, who oversees the department of atomic energy, told lawmakers that the bill — which has been dubbed Sustainable Harnessing and Advancement of Nuclear Energy for Transforming India — seeks to modernize India’s nuclear framework in line with technological, economic and energy realities. It also retains and strengthens core safety, security and regulatory safeguards.
“India’s role in geopolitics is increasing. And if we have to be a global player effectively, we have to live up to global benchmarks, follow global parameters and adopt global strategies,” Singh said in the lower house, adding that the legislation was necessary to address the country’s growing energy needs.
India wants more nuclear power and has pledged over $2 billion in recent months toward research and allied activities. Nuclear power is a way to make electricity that doesn’t emit planet-warming gases, although it does create radioactive waste.
India is one of the world’s biggest emitters of planet-heating gases and over 75 percent of its power is still generated by burning fossil fuels, mostly coal. India wants to install 100 gigawatts of nuclear power by 2047 — enough to power nearly 60 million Indian homes a year.
Energy experts say that for the world to move away from carbon-polluting fuels like coal, oil and gas, sources like nuclear that don’t rely on the sun and the wind — which aren’t always available — are needed. But some are skeptical about India’s ambitions as the country’s nuclear sector is still very small, and negative public perceptions about the industry remain.
Opposition parties flagged concerns related to several provisions of the bill and urged the government to refer it to a parliamentary panel for examination. The government didn’t adhere to the request.
“The bill doesn’t have sufficient safeguards when it comes to mitigating the bad health of those impacted by living in areas closer to nuclear plants,” Ashok Mittal, a lawmaker from the opposition Aam Admi Party, told The Associated Press.
G. Sundarrajan, an anti-nuclear energy activist, called the bill a “disastrous law,” saying it takes away essential safeguards that are needed to make sure companies invest in safety and reduce the chances of a major disaster that can impact millions from occurring.
“It also provides little recourse for any Indian citizen to claim damages from nuclear companies even if they are affected by radiation leaks or suffer from any other health impact as a result of a nuclear plant in their region,” he said.