Italian scientists claim world-first coronavirus vaccine breakthrough

An Italian coronavirus vaccine has antibodies generated in mice that work on human cells, according to tests carried out at Rome’s infectious-disease Spallanzani Hospital. (Reuters/File Photo)
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Updated 05 May 2020
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Italian scientists claim world-first coronavirus vaccine breakthrough

  • A coronavirus disease (COVID-19) candidate vaccine has neutralized the virus in human cells for the first time

ROME: An Italian coronavirus vaccine has antibodies generated in mice that work on human cells, according to tests carried out at Rome’s infectious-disease Spallanzani Hospital.

Luigi Aurisicchio, CEO of  Takis, the firm developing the medication, said that a coronavirus disease (COVID-19) candidate vaccine has neutralized the virus in human cells for the first time.

“This is the most advanced stage of testing of a candidate vaccine created in Italy,” Aurisicchio told the Italian newsagency ANSA. “Human tests are expected after this summer,” he added.

“According to Spallanzani Hospital, as far as we know we are the first in the world so far to have demonstrated a neutralization of the coronavirus by a vaccine. We expect this to happen in humans too,” said Aurisicchio.

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He explains that Takis is exploring “more interesting technological platforms with LineaRx, an American company.

“We are working hard for a vaccine coming from Italian research, with an all-Italian and innovative technology, tested in Italy and made available to everyone. In order to reach this goal we need the support of national and international institutions and partners who may help us speed up the process.”

Aurisicchio added: “This is not a competition. If we join our forces and skills together we can all win against coronavirus.”

Italian researchers describe the results “encouraging and well beyond expectations.”

After a single vaccination, the mice developed antibodies that can block the virus from infecting human cells, Aurisicchio said.

After observing that the five vaccine candidates generated a large number of antibodies, researchers selected the two with the best results.

Serum was isolated from the antibody-rich blood; it was then analyzed in the virology laboratory of the Spallanzani Institute, one of the most advanced establishments in Europe. The next step now is to understand how much the immune response lasts.

All of the vaccine candidates currently being developed are based on the material genetic of DNA protein “spike”, the molecular tip used by the coronavirus to enter human cells.

They are injected with the so-called “electroporation” technique, which consists of an intramuscular injection followed by a brief electrical impulse, helping the vaccine break into the cells and activating the immune system.

Researchers believe that this makes their vaccine particularly effective for generating functional antibodies against the “spike” protein, in particular in the lung cells, which are the most vulnerable to coronavirus.  

“So far, the immunity generated by most of our five vaccine candidates has an effect on the virus. We expect even better results after the second vaccination,” said Dr Emanuele Marra from Takis.

Marra added that those vaccine candidates could adapt to any COVID-19 evolutions and its possible mutations.

“We are already working on a trial version in case the virus accumulates mutations and becomes invisible to the immune system. For this purpose, we use the same concept we use in developing cancer vaccines,” he said.


Belgian agency aid worker dies in Gaza — minister

Updated 12 sec ago
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Belgian agency aid worker dies in Gaza — minister

BRUSSELS: An aid worker who was part of Belgium’s development aid efforts died in an Israeli strike on Gaza, the country’s development minister, Caroline Gennez, said on Thursday.
“It is with deep sadness and horror that we learn of the death of our colleague Abdallah Nabhan (33) and his seven-year-old son Jamal, last night, following a bombardment by the Israeli army in the eastern part of the city of Rafah,” the minister said in a statement.

Ukraine, Russia exchange fire, at least seven dead

Updated 2 min 59 sec ago
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Ukraine, Russia exchange fire, at least seven dead

The uptick in civilian deaths came as Russian forces are pressing in hard in the eastern Donetsk region of Ukraine
A Ukrainian attack drone left two dead in Zaporizhzhia and two more were killed by Ukranian artillery fire in Kherson

MOSCOW: Ukrainian and Russian forces exchanged drone and artillery fire on Thursday, leaving at least seven dead, regional officials on both sides of the frontline announced.
The uptick in civilian deaths came as Russian forces are pressing in hard in the eastern Donetsk region of Ukraine, ahead of events in Moscow on May 9, hailing the Soviet Union's victory in World War II.
A Ukrainian attack drone left two dead in the southern region of Zaporizhzhia and two more were killed by Ukranian artillery fire in the southern Kherson region, officials said.
The Kremlin claimed to have annexed both regions in late 2022 even though Russian forces are still battling to gain full control over them.
"A man and a woman were killed as a result of a strike on a civilian car. Their four young children were orphaned," the Russian-installed head of Zaporizhzhia, Evgeny Balitsky, wrote on social media.
He said the children would be taken into care and provided with psychological assistance.
The Russian head of the Kherson region, Vladimir Saldo, said separately that two more people were killed by Ukrainian fire in the village of Dnipryany.
The two frontline regions saw intense bouts of fighting in 2022 and the summer of 2023, when Ukraine launched a counteroffensive that failed to meet expectations in Zaporizhzhia.
The brunt of the fighting has since moved to the eastern Donetsk region, which is also claimed by Moscow as Russian territory.
The Ukrainian head of the Donetsk region, Vadim Filashkin, said three people had been killed in separate bouts of shelling in the villages of Udachne, where two people were killed, and in Kurakhivka, where one person was killed.
"The final consequences of the shelling have yet to be determined," he said.

Keralites in Gulf take ‘vote flights’ to join India’s mammoth polls

Updated 10 min 25 sec ago
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Keralites in Gulf take ‘vote flights’ to join India’s mammoth polls

  • ‘Vote flights’ are special chartered flights bringing Keralites home to cast ballots
  • Kerala is the single main place of origin of Indian expats living in Gulf countries

NEW DELHI: Tens of thousands of Keralites working in Gulf countries are flying home to cast their ballots as the southern Indian state opens for voting on Friday in the world’s biggest general election.

India’s seven-phase polls started on April 19 and take place over the next six weeks, with more than 968 million people registered to vote.

Some states are completing the process in a day, and others have it spread out in several phases. Kerala is joining other 12 states, which according to the schedule go to the polls on April 26.

Indian nationals living overseas have been allowed to vote since 2011 and have to register with both the Election Commission of India and Indian embassies in their countries of residence. Their names will then appear on the voters’ list, but to cast their ballots, they still need to be physically present in their constituencies.

India has one of the world’s largest diasporas, especially in GCC countries, where at least 9 million Indian expats live and work. The southwestern coastal state of Kerala is the single main place of their origin. Some 3.5 million Keralites reside in Saudi Arabia, Oman, Kuwait, Qatar, Bahrain and the UAE.

“I think about 30,000 people have come from Saudi Arabia alone to vote. Not all of them have come on ‘vote viman’ (vote flights). Some have also come by regular flights,” said Iqbal Cheri, a marketing professional working in Dammam, who reached Kerala on Thursday.

Cheri referred to the flights that have been bringing citizens home to participate in Friday’s polls.

“They bring voters only and they are mostly chartered flights,” he said. “We have come here to vote and save our democracy and secularism. It’s an important election and we all need to vote to save the nation.”

His compatriot, Shareef Chola Paramdil, who works as a marketing head of a hospital in Dammam, said these election flights have been bringing Saudi Arabia-based Kerala voters home for the past few days.

“Last week, also three chartered flights came from Saudi Arabia,” he said.

“People who come on the chartered flights pay less compared to the regular flights, as group booking brings down the fare. Besides, these people don’t get more than a few days of leave. So, they come and cast their votes and leave the next day.”

There are 543 contested seats in the lower house of parliament. The party or coalition that wins at least 272 is going to form the government. The state of Kerala will contribute 20.

For Paramdil, the election is particularly important as a Muslim because incumbent Prime Minister Narendra Modi and his ruling Bharatiya Janata Party have been accused by the opposition and minority groups of marshaling majoritarian Hindu sentiment.

Critics say that India’s tradition of diversity and secularism has been under attack since Modi took power a decade ago and that his party has been fostering religious intolerance and discrimination.

“We want a government that does not discriminate in the name of religion, and we have been troubled by the politics of division that the government in Delhi has been practicing ever since it came to power in 2014,” Paramdil said.

Both Keralite Muslims and Hindus — like Gokul Padnabhan, a Kuwait-based professional in the oil and gas industry — see the election as an important exercise of their democratic rights.

“It’s very important to be here this time. That’s why I came for the vote,” Padnabhan said. “The vote will help us find the right person to rule us for the next five years.”

One of the organizations helping expat voters charter flights in Gulf countries is the Kerala Muslim Cultural Centre, an overseas wing of the Indian Union Muslim League.

“I feel around 100,000 people have come from the Gulf region to vote in this election,” said Ahamed Saju, head of the IUML’s student federation.

“Why they came is because this is a very crucial election this time ... Each and every vote is important. So, they thought that this time to protect our democracy, protect our constitution, protect our values and protect our secular credentials and the secular fabric of the country.”


Bangladeshis pray for rain as heatstroke deaths rise

Muslims offer special prayers for rains, in Dhaka on April 24, 2024. (AFP)
Updated 46 min 3 sec ago
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Bangladeshis pray for rain as heatstroke deaths rise

  • Country is reaching limit of adaptability to extreme weather, report warns
  • Heatwave has shut schools for 33m Bangladeshi children

DHAKA: Thousands of Bangladeshis have gathered in Dhaka to pray for rain in the middle of an extreme hot spell that has put health authorities on heatstroke alert.

The weather across the region is usually hot across the region in April before the summer monsoon season, but this year temperatures have been unusually high, reaching 42 degrees Celsius in parts of Bangladesh.

The country has been on alert since last week, as the punishing heatwave has disrupted agriculture, raised the risk of health complications and forced schools to close for 33 million children.

As the Bangladesh Meteorological Department renewed its warning that the heatwave is likely to persist during the weekend — or until a new notice is issued — thousands of people in Dhaka prayed on Wednesday and Thursday for relief.

They gathered in city mosques and rural fields to pray for rain.

“Special prayers for rain have been organized in many parts of Dhaka on Thursday. Thousands of people joined these prayers ... in addition to that, a special prayer for rain, which Muslims around the world have practiced since the days of the Prophet Muhammad, has taken place in many parts across the country,” Motiur Rahman Akand, spokesperson of the Bangladesh Jamaat-e-Islami, the country’s largest religious political party, which organized the prayers, told Arab News.

“When there is a natural crisis, especially drought, which causes severe suffering for human beings and all other living creatures, people should seek help from the Almighty to get relief from this situation.”

Hospitals were on high alert as at least 20 people died from heatstroke in the past five days alone.

“We have been preparing quite ahead for managing heatwave-related patients ... all the government health facilities are guided not to admit any other patients unless it’s an emergency,” Dr. Moinul Ahsan, director of the hospital wing of the Directorate General of Health Services, told Arab News.

“We are on alert and monitoring the situation closely. Working-class people are suffering most amid this heatwave ... children, pregnant women and the elderly are also most vulnerable in this situation.”

Bangladesh’s geography and low-lying delta topography make it particularly vulnerable to the adverse effects of climate change, and for the past two decades, the country has launched various environmental schemes to mitigate the worsening situation.

Ranking among the 10 countries most prone to climate devastation, Bangladesh has been recognized as a global leader in adaptation and resilience, and in 2005 was one of the first least-developed countries to launch a national adaptation program of action.

A report released in February by the International Centre for Climate Change and Development, a leading research institute in Dhaka, warned that Bangladesh is reaching the limit of its ability to adapt to extreme weather.


Turkiye offers Iraq technical help to bolster border security

Updated 25 April 2024
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Turkiye offers Iraq technical help to bolster border security

  • A delegation from Iraq earlier visited Turkiye to examine the border security systems that Turkiye offered to provide
  • Discussions for security cooperation still under way

ANKARA: Turkiye is in discussions with Iraq to provide technical assistance to Baghdad for securing its borders to prevent movements of outlawed Kurdistan Workers Party (PKK) militants around the region, a Turkish defense ministry official said on Thursday.
Turkish President Tayyip Erdogan visited Baghdad and Irbil this week as Ankara ramped up cross-border operations against PKK militants based in mountainous, mainly Kurdish northern Iraq.
The two countries agreed to a strategic framework agreement overseeing security, trade and energy as well as a defense cooperation deal during the visit.
“We told our counterparts that Turkiye is ready to provide assistance to Iraq on border security systems,” the Turkish official told reporters.
A delegation from Iraq earlier visited Turkiye to examine the border security systems that Turkiye offered to provide, the official also said, adding that the discussions for security cooperation were still under way.
During a joint press conference with Erdogan on Monday, Iraqi Prime Minister Mohammed Shia Al-Sudani said the two countries would cooperate to bolster border security, without mentioning the PKK specifically.
The PKK took up arms against the Turkish state in 1984 and is designated a terrorist organization by Ankara and its Western allies. Turkiye has conducted a series of cross-border operations against the group in northern Iraq since 2019.