Cancer breakthrough by Lebanese doctor in the US

Foods identified by nutritionists to be rich in vitamin D. (Shutterstock image)
Updated 10 June 2019
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Cancer breakthrough by Lebanese doctor in the US

  • Study conducted by Dr. Tarek Haykal suggests 'sunshine' vitamin D can help patients live longer
  • The number of people in the Middle East with cancer is expected to double by 2030

CHICAGO: Adding vitamin D to diets can help cancer patients live longer, according to a study by a Lebanese doctor in the US.
The number of people in the Middle East with cancer is expected to double by the year 2030, with cancer of the breast, colon and lungs as the primary causes.
In the US, cancer is the second most leading cause of death.
But Dr. Tarek Haykal, 27, who is completing his residency in internal medicine at the Hurley Medical Center at Michigan State University in Flint, has released a study suggesting vitamin D carries some cancer benefit, not just for people in the Middle East but throughout the world.

Dr. Haykal and his team conducted a meta-analysis study involving 79,000 patients. The findings suggest  that a steady supplement of vitamin D for at least three years can help cancer patients live longer.




Dr. Tarek Haykal’s study points to a prolonged life for patients. (Supplied photo)

This works out to almost a 13 percent drop in cancer patient mortality.
The study was presented at the annual conference of the American Society of Clinical Oncology in Chicago recently.

"Vitamin D had a significant effect on lowering the risk of death among those with cancer, but unfortunately the study didn’t show any proof that it could protect against getting cancer," said Dr. Haykal, who is a lead author of the study.
The other doctors in the research team were Varun Samji, Yazan Zayed, Inderdeep Gakhal, Vijay Veerapaneni, Michele Obeid, Babikir Kheiri, Sunil Badami, Ghassan Bachuwa and Rizwan Danish.
"The point we tried to get at is to see if vitamin D had any benefit for cancer patients, mainly in primary prevention," said Dr Haykal.
"When we say primary prevention, we are talking about normal healthy individuals in the community, whether taking vitamin D really affects their cancer outcomes."
Three years of vitamin D supplements "were enough," he said.
"Mainly the benefit was in cancer-related mortality. So we tried to say there is a decrease in possible cancer deaths among patients taking vitamin D versus others.
"Does it mean that we should go around telling people to take vitamin D? Yes. We do need more awareness and we do encourage people to take vitamin D."
Vitamin D supplements have been studied as a primary prevention for illnesses including cardiovascular disease, osteoporosis, diabetes mellitus and cancer, Dr Haykal said.
Now it is being taken more seriously in addressing cancer.
"Global attention has never been on vitamin D, but now we are learning more and more that vitamin D is important to the health of your bones, and to your health in general," he said.
"We have more evidence that vitamin D has a lot of benefits, and we encourage patients and people in general to ensure they maintain good vitamin D levels."
Vitamin D —  "the sunshine vitamin" — is derived mainly from exposure to sunlight, but also comes from diets that include fish, mushrooms and egg yolk.




Cancer is the second most common cause of death in the US after heart disease. Recent studies suggest vitamin D supplements can extend patients’ lives. (Shutterstock)

But even with this diet and exposure to sunshine, deficiencies still occur, he said.
Haykal, who was born in Lebanon and trained in medicine at the Lebanese University in Beirut, began his three-year residency training at Hurley in 2017, so the impact of cancer on people in the Middle East is important to him.
"There is some data suggesting that despite the Middle East being one of the most sun-exposed areas of the world, we are still quite deficient in vitamin D," he said.
"Vitamin D deficiency is an important topic now, worldwide. Hence, the importance of the supplementation that we spoke of in our research."
Haykal said he has always been driven by a desire to help those in need. "After going to medical school, I was always interested only in the sickest patients of all," he said.
"I have always had a lot of passion and energy for those who are medically ill, like the ones who have cancer or who are in an intensive care unit," he said.
"So that is where I started leaning toward people who really needed my help and who needed energy and hope. I started focusing on oncology and this passion kept growing. After finishing medical school, I almost knew that I wanted to do internal medicine to pursue oncology."
Inspired by his colleagues and mentors, Haykal has published 30 medical papers during his two years at the Hurley Medical Center.
"Vitamin D came to me as any idea would come to anyone," he said, adding that he began researching the subject with colleagues.
"Combining the data, we found that that vitamin D supplementation for at least three years gave the general population cancer-related mortality benefits and decreased risks, but it did not have much effect on the incidence of cancer, unfortunately."
Dr. Haykal recommends people have their vitamin D levels checked during routine health examinations.
"People are not as aware of vitamin D because it doesn't necessarily cause immediate medical issues. Rather, it is a chronic process. So, if you are deficient, you are never going to have any symptoms that will alarm you.
"Rather, you have to check with your physician and make sure that you are adequately supplemented.
"Staying healthy does not mean you have to obsess about everything you eat or drink. But adopting a healthy lifestyle is important."


Finance firms urge ambitious action on plastic pollution

Updated 19 April 2024
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Finance firms urge ambitious action on plastic pollution

  • Curtailing the estimated 400 million metric tonnes of waste produced every year is a crucial part of efforts to protect biodiversity, with microplastics found everywhere from the mountainous Himalayas to staple foods and even human blood

LONDON: A group of 160 financial companies on Friday urged governments to agree a treaty to end plastic pollution that would help spur private sector action, ahead of the next round of global talks in Canada.
The fourth meeting of the Intergovernmental Negotiating Committee on Plastic Pollution (INC-4) is due to be held in Ottawa next week to lay the groundwork for an eventual deal before the end of the year.
Curtailing the estimated 400 million metric tonnes of waste produced every year is a crucial part of efforts to protect biodiversity, with microplastics found everywhere from the mountainous Himalayas to staple foods and even human blood.
To help fix the problem, the finance firms, which include Britain’s biggest investor Legal & General Investment Management and Canadian pension investor CDPQ, called for a policy framework backed up by binding rules.
Among specific steps, the group called for the treaty to set an objective for all public and private finance to be consistent with the goal of eliminating plastic pollution, similar to that in the Paris climate agreement and the Kunming-Montreal global biodiversity framework.
It also called for companies to assess and disclose plastic-related risks and opportunities; clearer plastic-related policies and targets from governments in areas like waste creating and recycling; and for further private investment to be directed to ending plastic pollution.
“A clear transition pathway laid out in the Treaty will help leverage finance at scale for this massive task of ending plastic pollution worldwide,” said Anne-Sophie Castelnau, global head of sustainability at ING, one of the signatories.
Steve Hardman, CEO of Plastic Collective, an NGO which designed the world’s first plastic waste reduction bond alongside Citi and the World Bank, welcomed the support but called for business to provide more financial solutions.
In January, the World Bank issued the $100 million bond to finance plastic-reduction projects in Ghana and Indonesia. Investors will be paid a rate linked to plastic removal credits generated by the projects.

 


Finnish PM: EU should help end migrant influx from Russia

Updated 19 April 2024
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Finnish PM: EU should help end migrant influx from Russia

  • European Commission President Ursula von der Leyen visits the border to assess security situation

HELSINKI: The EU should take measures to help Finland stop an influx of migrants via Russia, Finnish Prime Minister Petteri Orpo said.

Finland last year shut its long border with Russia amid a growing number of arrivals from countries including Syria and Somalia.
It accused Moscow of weaponizing migration against the Nordic nation and the EU, an assertion the Kremlin denies.
Finland’s government has closed eight of its nine checkpoints with Russia.
The only one that remains open is dedicated to rail travel and cargo trains mainly run through it.
“We are preparing our legislation, but we also need EU measures,” Orpo said, without elaborating, after visiting the Nordic country’s border with European Commission President Ursula von der Leyen.
Von der Leyen told the same press conference that the EU Commission was working closely with the migrants’ countries of origin, agreeing with Finland’s position.
“What we see is that a state is instrumentalizing poor people to put pressure on another state, so that is a clear security issue,” she said.
She said that the measures taken to deal with migrants from Russia must balance protecting the security of borders and international obligations.
Following Poland and Lithuania’s example on their borders with Belarus, the Finnish government is drafting legislation allowing border guards to block asylum seekers entering the country from Russia.
“We all know how (Russian President Vladimir) Putin and his allies instrumentalize migrants to test our defenses and to try to destabilize us,” von der Leyen told officials.
“Now Putin is focusing on Finland, and this is no doubt in response to your firm support of Ukraine and your accession to NATO.”
Von der Leyen and Orpo flew in a Finnish helicopter over the landscape of forests and towns on the border.
Von der Leyen is campaigning as a conservative European People’s Party bloc member for a second term in office as head of the EU’s powerful executive branch.
Security is a top EPP theme before the June 6-9 European Parliament elections.
Most of the migrants hail from the Middle East and Africa.
Most of them have sought asylum in Finland, a member of the EU and NATO with a population of 5.6 million.
Finland joined NATO in April 2023, ending decades of neutrality after the country’s defeat by the Soviet Union in the Second World War.
In March, Sweden also became a member of the trans-Atlantic alliance.
The move dealt a major blow to Putin, with a historic realignment of Europe’s post-Cold War security landscape triggered by Moscow’s offensive against Ukraine.

 


US sanctions ally of Israeli minister, entities backing ‘extremist’ settlers

Updated 10 min 14 sec ago
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US sanctions ally of Israeli minister, entities backing ‘extremist’ settlers

  • Move comes as West Bank sees some of its worst violence perpetrated by settlers against Palestinians since Gaza war

WASHINGTON: The United States on Friday imposed sanctions on an ally of Israel’s far-right national security minister and two entities that raised money for Israeli men accused of settler violence, the latest actions aimed against those Washington blames for an escalation of violence in the Israeli-occupied West Bank.
The sanctions, in addition to those already imposed on five settlers and two unauthorized outposts already this year, are the latest sign of growing US frustration with the policies of Israeli Prime Minister Benjamin Netanyahu.
The moves on Friday, which freeze any US assets held by those targeted and generally bar Americans from dealing with them, hit two organizations that launched fundraising campaigns to support settlers accused of violence and targeted by previous sanctions, the Department of the Treasury said in a statement.
The Biden administration’s moves against Israeli settlers have upset right-wing members of Netanyahu’s governing coalition who support the expansion of Jewish settlements and ultimately the annexation of the West Bank, where Palestinians envisage a future state.
They come as the complex relationship between Washington and its ally Israel is tested by the war in Gaza and as the Biden administration urges Israel to show restraint in responding to retaliatory strikes by Iran.
Washington sanctioned Ben-Zion Gopstein, founder and leader of the right-wing group Lehava, which opposes Jewish assimilation with non-Jews and agitates against Arabs in the name of religion and national security. Gopstein has said Lehava has 5,000 members.
State Department spokesperson Matthew Miller said members of the group had engaged in “destabilizing violence affecting the West Bank.”
“Under Gopstein’s leadership, Lehava and its members have been involved in acts or threats of violence against Palestinians, often targeting sensitive or volatile areas,” Miller said in a statement, warning of additional steps if Israel does not take measures to prevent extremist attacks amid an escalation of violence in the West Bank in recent days.
The European Union also said on Friday it had agreed to take sanctions against Lehava and other groups linked to violent settlers.
A spokesperson for Israel’s embassy in Washington did not immediately respond to a request for comment.
Gopstein, the most prominent Israeli figure targeted by US sanctions, is a close associate of and has family ties to National Security Minister Itamar Ben-Gvir, who himself lives in a West Bank settlement.
Ben-Gvir, like Gopstein, was a disciple of the late Meir Kahane, an ultranationalist rabbi whose Kach movement was listed by Washington as a specially designated global terrorist organization.
Ben-Gvir on Friday slammed what he called harassment against Lehava and “our dear settlers who have never engaged in terrorism or hurt anyone,” labeling the allegations against them a “blood libel” by Palestinian groups and anarchists.
“I call on Western countries to stop cooperating with these antisemites and end this campaign of persecution against the pioneering Zionist settlers,” Ben-Gvir said in a statement released by his office.
CROWDFUNDING
Since the 1967 Middle East war, Israel has occupied the West Bank of the Jordan River, which Palestinians want as the core of an independent state. It has built Jewish settlements there that most countries deem illegal. Israel disputes this and cites historical and Biblical ties to the land.
The Biden administration in February said settlements were inconsistent with international law, signaling a return to long-standing US policy on the issue that had been reversed by the previous administration of Donald Trump.
One entity targeted on Friday, Mount Hebron Fund, launched an online fundraising campaign that raised $140,000 for settler Yinon Levi, the Treasury said, after he was sanctioned on Feb. 1 for leading a group of settlers that assaulted Palestinian and Bedouin civilians, burned their fields and destroyed their property.
It said the second entity, Shlom Asiraich, raised $31,000 on a crowdfunding website for David Chai Chasdai, who the United States sanctioned for initiating and leading a riot that included setting vehicles and buildings on fire and causing damage to property in the Palestinian town of Hawara, resulting in the death of a Palestinian civilian.
“These types of enforcement actions against entities helping violent settlers evade US sanctions are what give sanctions teeth,” said Michael Schaeffer Omer-Man, director of research for Israel-Palestine at Democracy for the Arab World Now, a human rights group that has highlighted efforts by supporters to evade sanctions against settlers.

 

 


Hindu-Muslim divisions sway voting in Indian district scarred by deadly riots

Updated 19 April 2024
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Hindu-Muslim divisions sway voting in Indian district scarred by deadly riots

  • Villages are largely self-segregated by religion in and around Muzaffarnagar in the most populous Uttar Pradesh state
  • Violent clashes broke out in 2013 after two Hindus stabbed Muslim youth to death, accusing him of harassing their sister

MUZAFFARNAGAR: Hindu-Muslim enmity made way for peace in an Indian district that saw deadly riots a decade ago but religious divisions still influence residents who voted on Friday in general elections in which Hindu nationalism is a key theme.

Villages are largely self-segregated by religion in and around Muzaffarnagar district, in the most populous northern state of Uttar Pradesh, but people say there is no longer tension between the majority Hindu and minority Muslim communities.

Violent clashes broke out here in 2013 after two Hindus stabbed a Muslim youth to death, accusing him of sexually harassing their sister. They were later beaten to death by a Muslim mob, which sparked riots that killed about 65 people, mostly Muslims, and displaced thousands.

Violence has not returned to the district known as the country's sugarcane-belt, but political divisions remain as Hindus typically vote for Prime Minister Narendra Modi's Bharatiya Janata Party (BJP) and Muslims for the opposition.

Modi's government has "controlled Muslims", said Ramesh Chand, a Hindu biscuit baker in Kairana city near Muzaffarnagar.

Critics accuse the nationalist BJP of targeting India's 200 million minority Muslims to please their hardline Hindu base - charges they deny.

Modi is widely expected to win a third term on the back of strong growth, welfare and his personal popularity despite some concern about unemployment, price rises and rural distress.

Chand said Modi had improved security in the region. "We can live in peace, whether or not we have jobs ... We can sleep with our doors open."

There were opposing views too.

In Jaula village, sugarcane farmer Mohammed Irfan, 50, said Modi's "high-handedness against Muslims" as well as unemployment and inflation were major reasons for him voting for the opposition Samajwadi Party.

Uttar Pradesh elects 80 lawmakers to the 543-member lower house of parliament, the most among all states, and a strong showing here is critical to the nationwide outcome.

Support for Modi was visible in Kutba Kutbi village, the epicentre of the 2013 riots.

Although there is "brotherhood" between the two communities now, nearly all Muslim families left the village after the riots, said Vinay Kumar Baliyan, 43, a farmer who said he supports Modi for promoting economic growth and raising India's stature globally.

But Irfan said Muslims are expected to vote in larger numbers this time as Eid celebrations this month brought many migrant workers and students home.


After Pakistan alert, WHO likely to issue wider warning on contaminated J&J cough syrup

Updated 19 April 2024
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After Pakistan alert, WHO likely to issue wider warning on contaminated J&J cough syrup

  • The UN health body said it puts out global medical product alerts to ‘encourage diligence’ by authorities
  • The WHO this week sent out alert on five batches of contaminated cough syrup ingredients found in Pakistan

LONDON: The World Health Organization is likely to issue a wider warning about contaminated Johnson and Johnson-made children’s cough syrup found in Nigeria last week, it said in an email.

Nigeria’s regulator recalled a batch of Benylin paediatric syrup last Wednesday, having found a high level of diethylene glycol in the product during routine testing.

The contaminant, alongside another closely related toxin, ethylene glycol, has been linked to the deaths of more than 300 children in Cameroon, Gambia, Indonesia and Uzbekistan since 2022, though there is no evidence that these incidents are linked with the latest recalls.

The UN health body said it puts out global medical product alerts to “encourage diligence” by national authorities and was likely to do so in this instance, “subject to confirmation of certain details from parties.”

The recalled batch of Benylin syrup was made by J&J in South Africa in May 2021, although Kenvue now owns the brand after a spin-off from J&J last year.

J&J has referred requests for comment to Kenvue. In an emailed statement on Friday, Kenvue said it had carried out tests on the batch recalled by Nigeria and had not detected either diethylene or ethylene glycol.

“We continue to work closely with health authorities and the WHO and are engaging with NAFDAC to understand their test results, including verifying the authenticity of the sampled product, the testing methodology used, and results reported by the agency,” the statement added.

Since Nigeria’s recall, five other African countries have also pulled the product from shelves — Kenya, Rwanda, Tanzania, Zimbabwe and South Africa, where the drug was made.

South Africa’s regulator has also recalled another batch of the syrup, which is used to treat coughs, hay fever and other allergic reactions in children.

Diethylene glycol is toxic to humans when consumed and can result in acute kidney failure, although there have been no reports of harm in the latest incident.

RAW MATERIALS

In the 2022 cases, the contamination in the syrups came from the raw materials used by manufacturers in India and Indonesia.

The WHO said it was collaborating with both the manufacturer and regulatory authority in South Africa to investigate the Benylin paediatric syrup, and had information on the source of the ingredients used. Kenvue has previously said it tested its ingredients before manufacture.

The agency said the possibility that the syrup was counterfeit was also “under consideration as part of investigations.”

Earlier this week the WHO sent out a separate alert on five batches of contaminated cough syrup ingredients found in Pakistan that appeared to have been falsely labelled as Dow Chemical products.

It was the first alert the WHO has sent on excipients — elements of a medicine other than the active pharmaceutical ingredient — rather than finished products, the agency confirmed on Friday.

The batches of propylene glycol were contaminated with ethylene glycol.

“It was critical for WHO to also alert manufacturers that may have been procuring this material to exercise more caution,” a WHO spokesperson said by email.

Propylene glycol is not an ingredient in Benylin paediatric syrup, a Kenvue spokesperson said on Friday.